Mehrnoush Vahid, Ismail Asmaa, Zakaria Ahmed, Elmansy Hazem, Shahrour Walid, Prowse Owen, Kotb Ahmed
Department of Urology, Northern Ontario School of Medicine, TBRHSC, 980 Oliver Road, Thunder Bay, Ontario, P7B 6V4, Canada.
J Surg Case Rep. 2021 Nov 11;2021(11):rjab501. doi: 10.1093/jscr/rjab501. eCollection 2021 Nov.
There is little research on the role of urethrectomy during cystectomy in patients with micropapillary bladder cancer (MPBC). We present two cases of MPBC cystectomy and suggest that urethrectomy be performed concurrently as a preventive measure. The first case involved a woman who had a mixed solid and papillary bladder tumour. An anterior pelvic exenteration was performed as well as a total urethrectomy. The T4a micropapillary variant tumour was confirmed by pathology. The second case involved a man with T1 MPBC who was treated with a BCG induction course. A recurrent muscle-invasive MPBC was discovered during follow-up. During the radical cystoprostatectomy, the urethra was spared. T2 MPBC was discovered through pathology. He had a urethrectomy 6 months later due to urethral bleeding, and the pathology revealed micropapillary cancer of the urethra.
关于微乳头型膀胱癌（MPBC）患者膀胱切除术中尿道切除术的作用，相关研究较少。我们报告了两例MPBC膀胱切除术病例，并建议作为预防措施同时进行尿道切除术。第一例患者为一名女性，患有实性和乳头状混合性膀胱肿瘤。进行了前盆腔脏器清除术及全尿道切除术。病理证实为T4a微乳头型变异肿瘤。第二例患者为一名T1期MPBC男性，接受了卡介苗诱导治疗。随访期间发现复发性肌层浸润性MPBC。在根治性膀胱前列腺切除术中，保留了尿道。病理检查发现为T2期MPBC。6个月后，他因尿道出血接受了尿道切除术，病理显示为尿道微乳头癌。
