Sideris Giorgos, Sapountzi Marilia C, Malamas Vangelis, Korres George, Delides Alexander, Nikolopoulos Thomas
Second Ear-Nose-Throat Department, Attikon University Hospital, National and Kapodistrian University of Athens School of Medicine, Athens, GRC.
Department of Infomatics, University of Peiraeus, Peiraeus, GRC.
Cureus. 2021 Oct 15;13(10):e18811. doi: 10.7759/cureus.18811. eCollection 2021 Oct.
Objective To investigate the possible correlation between benign paroxysmal positional vertigo (BPPV), seasonality, and climatic variations as indicators of vitamin D deficiency, since otoconia are calcium carbonate crystals. Methods This is a study of patients who received the diagnosis of BPPV from September 2015 to August 2019. Gender, age, and month of diagnosis were factors recorded and analyzed. The cut-off age of 50 years is used to include osteoporotic patients and postmenopausal women. Meteorological and climatic data of latitude, temperature, sunshine hours, humidity, precipitation, wind force, atmospheric pressure, and horizontal solar irradiance were collected. Results Four hundred and eighty-five patients were included in the study; 206 were male (42%) and 279 were female (58%). The mean age was 57.8±15.4 and 54.9±13.9, respectively; 192 patients were ≤50 years old (121 female and 71 male) and 293 patients were over 50 years old (135 male and 158 female). A statistical significance in seasonal variation during autumn months was demonstrated (p-value= 5.2 e-05, z-statistic: 9.8164). There was no statistical correlation between the median number of BPPV patients and the median sunshine hours per month, horizontal solar irradiance, or other climatic variables. Conclusions Our study demonstrates seasonality in BPPV patients in Greece but no correlation between BPPV and climatic variations as a proxy for Vitamin-D levels was documented.
目的 鉴于耳石是碳酸钙晶体，探讨良性阵发性位置性眩晕（BPPV）、季节性和气候变化作为维生素D缺乏指标之间的可能相关性。方法 本研究纳入2015年9月至2019年8月期间被诊断为BPPV的患者。记录并分析性别、年龄和诊断月份等因素。采用50岁的年龄界限纳入骨质疏松患者和绝经后女性。收集纬度、温度、日照时长、湿度、降水量、风力、气压和水平太阳辐照度等气象和气候数据。结果 本研究共纳入485例患者；男性206例（42%），女性279例（58%）。平均年龄分别为57.8±15.4岁和54.9±13.9岁；192例患者年龄≤50岁（女性121例，男性71例），293例患者年龄超过50岁（男性135例，女性158例）。秋季的季节变化具有统计学意义（p值=5.2×10⁻⁵，z统计量：9.8164）。BPPV患者中位数与每月日照时长中位数、水平太阳辐照度或其他气候变量之间无统计学相关性。结论 我们的研究表明希腊BPPV患者存在季节性，但未发现BPPV与作为维生素D水平替代指标的气候变化之间存在相关性。
