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支架置入术在布加综合征中的应用及疗效

The application and efficacy of stent place for Budd-Chiari syndrome.

作者信息

Zu Maoheng, Xu Hao, Gu Yuming, Zhang Qingqiao, Wei Ning, Xu Wei, Cui Yanfeng

机构信息

The Affiliated Hospital of Xuzhou Medical University.

出版信息

J Interv Med. 2019 Apr 30;1(3):170-175. doi: 10.19779/j.cnki.2096-3602.2018.03.07. eCollection 2018 Aug.

Abstract

To evaluate the application value and efficacy on stent place for Budd-Chiari syndrome (BCS). From January 1990 to May 2017, 2228 patients with BCS were admitted to our institution. The mean age was 43.3 years. Stents were placed in inferior vena cava (IVC), hepatic vein (HV), or both after balloon dilation. During follow-up period, the patency of stent was evaluated by ultrasound regularly and the clinic sign was surveyed by letter, telephone or clinic visit. The restenosis of stent were treated with balloon dilatation and thrombolysis to restore the its function. IVC type was diagnosed in 1492 cases, HV type in 510 cases, and mixed type in 226 cases. Eighteen patients aborted treatment because of economic reasons, advanced liver cancer, severe scoliosis, or both bilateral iliac veins and total IVC occlusion. Among the other 2210 cases who underwent endovascular therapy, stents were implanted into IVC in 339 cases, HV in 97 cases, mixed type in 64 cases. The rate of restenosis in IVC stent was 11.50% (39/339). After repeat angioplasty, the long-term patency rate reached to 98.12%. The incidence of HV occlusion caused by IVC stent was 12.09% (n = 41). Restenosis occurred in 47 cases (48.45%) after HV stent placement. However, the 5-year patency rate was 91.75% (89/97) after repeat dilatation and stent re-implantation. The incidence of IVC obstruction caused by HV was 3.33% (3 cases). IVC stent placement appears to be an effective treatment for the cases of IVC segmental occlusion, and at the same time, the stent has the dual role of compression and fixation of thrombus and support of lumen. The HV and accessory hepatic vein obstruction could happen when the IVC stent crossed these veins ostium. The incidence of the stent restenosis in the HV was higher than that in the IVC.

摘要

评估支架置入术治疗布加综合征(BCS)的应用价值及疗效。1990年1月至2017年5月,我院收治2228例BCS患者。平均年龄43.3岁。在球囊扩张后,将支架置入下腔静脉(IVC)、肝静脉(HV)或两者。随访期间,定期通过超声评估支架通畅情况,并通过信件、电话或门诊复查临床症状。对支架再狭窄采用球囊扩张及溶栓治疗以恢复其功能。IVC型1492例,HV型510例,混合型226例。18例患者因经济原因、晚期肝癌、严重脊柱侧弯或双侧髂静脉及全段IVC闭塞而中止治疗。在其他2210例行血管内治疗的患者中,339例将支架置入IVC,97例置入HV,64例置入混合型。IVC支架再狭窄率为11.50%(39/339)。再次血管成形术后,长期通畅率达98.12%。IVC支架导致HV闭塞的发生率为12.09%(n = 41)。HV支架置入后47例(48.45%)发生再狭窄。然而,再次扩张及重新置入支架后,5年通畅率为91.75%(89/97)。HV导致IVC梗阻的发生率为3.33%(3例)。IVC支架置入术似乎是治疗IVC节段性闭塞病例的有效方法,同时,支架具有压迫和固定血栓以及支撑管腔的双重作用。当IVC支架穿过这些静脉开口时,可能会发生HV及副肝静脉梗阻。HV支架再狭窄的发生率高于IVC。

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