[Pre- and postoperative chemotherapy in bone and soft tissue tumors].

Adjuvant chemotherapy is efficacious in Ewing's sarcoma, and in osteosarcoma most data support its beneficial effect. There is evidence to suggest efficacy of adjuvant treatment in high-grade malignant soft tissue sarcomas. Neoadjuvant chemotherapy can be used as prediction for the efficacy of further adjuvant chemotherapy and may facilitate resection in osteosarcoma.