Chomette G, Auriol M, Magnier P, Szpirglas H, Guilbert F, Vaillant J M
Service d'Anatomie pathologique, Hôpital de la Pitié, Paris.
Rev Stomatol Chir Maxillofac. 1987;88(5):345-9.
The 4 cases of malignant xanthogranuloma reported here are peculiar because of their unusual localization in the cervico-facial area and of their good outcome (3 patients are alive without recurrence more than 6 years after chemotherapy and radiotherapy). Besides the histological study, the 4 cases were examined by immunohistochemical methods : vimentin was positive in 20 to 40% of cells and lysozyme in 5 to 15% of cells. In addition, one case was studied by electron microscope which showed the polymorphism of tumoral cells.
本文报道的4例恶性黄色肉芽肿病例较为特殊，因其病变部位异常位于颈面部，且预后良好（3例患者在化疗和放疗后存活超过6年无复发）。除了组织学研究外，还对这4例病例进行了免疫组化检查：波形蛋白在20%至40%的细胞中呈阳性，溶菌酶在5%至15%的细胞中呈阳性。此外，对1例病例进行了电子显微镜检查，结果显示肿瘤细胞具有多形性。
