Zhao Ziqiang, Zhao Jinwei, Zhang Simeng, Zhang Guang, Chen Weiben, Yang Zongfan, Zhang Ting, Chen Long
Department of Chemistry and Tianjin Key Laboratory of Molecular Optoelectronic Science, Tianjin University, Tianjin 300072, China.
Institute of Molecular Plus, Tianjin University, Tianjin 300072, China.
Nanoscale. 2021 Dec 2;13(46):19385-19390. doi: 10.1039/d1nr05758h.
Topology modulation of covalent organic frameworks (COFs) still remains barely explored, probably due to the lack of appropriate building blocks. A "two-in-one" strategy applies bifunctional monomers to endow ideal stoichiometry and has recently demonstrated great potential in the facile preparation of highly crystalline two-dimensional (2D) COFs with different topologies. Herein, we employ this approach to modulate the topology of 2D COFs by varying the solvents or the monomer concentrations. To our delight, 2D COFs featuring a Kagome () lattice with both hexagonal and triangular dual pores (DP) or featuring a rhombic square () single pore (SP) structure can be selectively formed by varying the solvents. Furthermore, adjusting the monomer concentrations also successfully tuned the topology of the COFs. In addition, the highly porous dual-pore COF showed potential applications for controlled drug delivery.
共价有机框架（COFs）的拓扑结构调控仍鲜有探索，这可能是由于缺乏合适的构建模块。一种“二合一”策略采用双功能单体来赋予理想的化学计量比，并且最近在简便制备具有不同拓扑结构的高结晶二维（2D）COFs方面展现出了巨大潜力。在此，我们采用这种方法通过改变溶剂或单体浓度来调控二维COFs的拓扑结构。令我们高兴的是，通过改变溶剂，可以选择性地形成具有六边形和三角形双孔（DP）的 Kagome（）晶格或具有菱形正方形（）单孔（SP）结构的二维COFs。此外，调整单体浓度也成功地调节了COFs的拓扑结构。此外，高度多孔的双孔COF在可控药物递送方面显示出潜在应用。
