Bianco S, Ferrara A, Bossi R, Moavero N E, Allegra L, Fumagalli G
Minerva Med. 1979 Jan 7;70(1):51-7.
The Authors studied lung mechanics, acid-base balance parameters, arterial blood pressure and pulse rate in five different groups of chronic obstructive lung disease patients, undergoing e.v. different bronchodilators. The drug were: 1. group: 500 gamma of orciprenalina; 2. group: 500 gamma of idrossi-fenil-orciprenalina; 3. group: 200 gamma of salbutamolo; 4. group: 100 gamma of trimetochinolo; 5. group: 500 gamma of terbutalina. The comparative analysis of bronchodilators, their cardiovascular effects and on acid-base balance indicate that mainly salbutamol and trimetochinol have negligeable adverse effects.
作者研究了五组慢性阻塞性肺疾病患者在静脉注射不同支气管扩张剂后的肺力学、酸碱平衡参数、动脉血压和脉搏率。这些药物分别是:1组:500微克间羟异丙肾上腺素;2组:500微克羟苯间羟异丙肾上腺素;3组:200微克沙丁胺醇;4组:100微克曲美托喹酚;5组:500微克特布他林。对支气管扩张剂及其心血管效应和酸碱平衡的比较分析表明,主要是沙丁胺醇和曲美托喹酚的不良反应可忽略不计。