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直接腹膜复苏在创伤患者中导致相似的腹腔内并发症发生率。

Direct Peritoneal Resuscitation in Trauma Patients Results in Similar Rates of Intra-Abdominal Complications.

机构信息

Division of Trauma and Acute Care, Department of Surgery, The Brody School of Medicine, East Carolina University, Greenville, North Carolina, USA.

Division of Surgical Research, Department of Surgery, The Brody School of Medicine, East Carolina University, Greenville, North Carolina, USA.

出版信息

Surg Infect (Larchmt). 2022 Mar;23(2):113-118. doi: 10.1089/sur.2021.262. Epub 2021 Nov 23.

Abstract

Trauma patients undergoing damage control surgery (DCS) have a propensity for complicated abdominal closures and intra-abdominal complications. Studies show that management of open abdomens with direct peritoneal resuscitation (DPR) reduces intra-abdominal complications and accelerates abdominal closure. This novel study compares intra-abdominal complication rates and the effect of DPR initiation in patients who received DPR and those who did not. A retrospective chart review was performed on 120 patients who underwent DCS. Fifty patients were identified as DCS with DPR, and matched to 70 controls by gender, race, age, body mass index (BMI), past medical history, mechanism of trauma, and injury severity score. The two groups of patients, those without DPR (-DPR) and those with DPR (+DPR), were similar in their characteristics. The +DPR group was more likely to have a mesh closure than the -DPR (14% and 3%; p = 0.022). The +DPR group took longer to have a final closure (3.5 ± 2.6 days vs. 2.5 ± 1.8; p = 0.020). Infection complications and mechanical failure of the closure technique were similar among the two groups. Timing of DPR initiation had no effect on closure type but did statistically increase the number of days to closure (initiation at first operation 2.8 ± 1.8 days vs. initiation at subsequent operations 6.0 ± 3.3 days; p ≤ 0.001). The use of DPR did not result in different outcomes in trauma patients. Therefore, traditional resuscitative measures for DCS may not be inferior to DCS with DPR. When choosing to use DPR, initiating it at the first operation could reduce the number of days to closure.

摘要

创伤患者接受损伤控制性手术(DCS)后容易出现腹部闭合困难和腹腔内并发症。研究表明,采用直接腹膜复苏(DPR)处理开放性腹部可减少腹腔内并发症并加速腹部闭合。本研究比较了接受 DPR 与未接受 DPR 的患者的腹腔内并发症发生率和 DPR 启动的效果。对 120 例接受 DCS 的患者进行了回顾性图表审查。将 50 例患者确定为 DCS 伴 DPR,并通过性别、种族、年龄、体重指数(BMI)、既往病史、创伤机制和损伤严重程度评分与 70 例对照进行匹配。未接受 DPR(-DPR)和接受 DPR(+DPR)的两组患者在特征上相似。+DPR 组比 -DPR 组更有可能采用网片闭合(14%和 3%;p=0.022)。+DPR 组最终闭合时间更长(3.5±2.6 天 vs. 2.5±1.8 天;p=0.020)。两组感染并发症和闭合技术的机械故障发生率相似。DPR 启动时间对闭合类型没有影响,但在统计学上增加了闭合时间(首次手术时 2.8±1.8 天 vs. 后续手术时 6.0±3.3 天;p≤0.001)。DPR 的使用并未导致创伤患者的不同结局。因此,DCS 的传统复苏措施可能并不逊于 DCS 加 DPR。选择使用 DPR 时,首次手术时启动可减少闭合时间。

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