Department of Chemistry, University at Buffalo, The State University of New York, Buffalo, New York 14260-3000, United States.
The Institute for Lasers, Photonics and Biophotonics, State University of New York at Buffalo, Buffalo, New York 14260, United States.
J Phys Chem B. 2021 Dec 9;125(48):13132-13136. doi: 10.1021/acs.jpcb.1c07659. Epub 2021 Nov 23.
Emission bands from thermally coupled states in lanthanide-doped nanoparticles have been studied for ratiometric nanothermometry in biological applications. Unfortunately certain factors such as water absorption distort the intensity, limiting the accuracy of ratiometric nanothermometry. However, the decay time of such states does not suffer from such distortions. We introduce the decay time of the H state in Yb, Tm-doped nanoparticles for improved nanothermometry. The strong 800 nm upconversion emission exists in the first biological transparency window. This is the first use of a single upconversion band for lifetime nanothermometry.
我们研究了掺杂镧系元素纳米粒子中热耦合态的发射带，以实现用于生物应用的比率型纳米测温。不幸的是，水吸收等因素会使强度发生扭曲，从而限制了比率型纳米测温的准确性。然而，这种状态的衰减时间不会受到这种扭曲的影响。我们为改进纳米测温而引入了 Yb、Tm 掺杂纳米粒子中 H 态的衰减时间。强烈的 800nm 上转换发射存在于第一个生物透明窗口中。这是首次使用单个上转换带进行寿命型纳米测温。
