RNA 加工：真菌剪接体打破常规。

RNA processing: Fungal spliceosomes break the mold.

机构信息

Department of Biochemistry, University of Wisconsin-Madison, Madison, WI 53706, USA.

Department of Biochemistry, University of Wisconsin-Madison, Madison, WI 53706, USA; Department of Chemistry, University of Wisconsin-Madison, Madison, WI 53706, USA.

出版信息

Curr Biol. 2021 Nov 22;31(22):R1482-R1484. doi: 10.1016/j.cub.2021.09.075.

DOI:10.1016/j.cub.2021.09.075

PMID:34813754

Abstract

Dozens of splicing factors work together in human cells to remove introns from nascent RNA transcripts. A new study reveals that spliceosomes from many distantly related fungal species are surprisingly similar to those found in human cells.

摘要

数十种剪接因子在人类细胞中协同工作，从新生 RNA 转录本中去除内含子。一项新的研究表明，许多亲缘关系较远的真菌物种的剪接体与在人类细胞中发现的剪接体惊人地相似。