New York State Office of Mental Health, NY.
New York State Office of Mental Health, NY; Department of Epidemiology and Biostatistics, University at Albany-SUNY, School of Public Health.
J Affect Disord. 2022 Feb 15;299:698-706. doi: 10.1016/j.jad.2021.11.035. Epub 2021 Nov 20.
Behavioral health outpatients are at risk for self-harm. Identifying individuals or combination of risk factors could discriminate those at elevated risk for self-harm.
The study population (N = 248,491) included New York State Medicaid-enrolled individuals aged 10 to 64 with mental health clinic services between November 1, 2015 to November 1, 2016. Self-harm episodes were defined using ICD-10 codes from emergency department and inpatient visits. Multi-predictor logistic regression models were fit on a subsample of the data and compared to a testing sample based on discrimination performance (Area Under the Curve or AUC).
Of N = 248,491 patients, 4,224 (1.70%) had an episode of intentional self-harm. Factors associated with increased self-harm risk were age 17-25, being female and having recent diagnoses of depression (AOR=4.3, 95%CI: 3.6-5.0), personality disorder (AOR=4.2, 95%CI: 2.9-6.1), or substance use disorder (AOR=3.4, 95%CI: 2.7-4.3) within the last month. A multi-predictor logistic regression model including demographics and new psychiatric diagnoses within 90 days prior to index date had good discrimination and outperformed competitor models on a testing sample (AUC=0.86, 95%CI:0.85-0.87).
New York State Medicaid data may not be generalizable to the entire U.S population. ICD-10 codes do not allow distinction between self-harm with and without intent to die.
Our results highlight the usefulness of recency of new psychiatric diagnoses, in predicting the magnitude and timing of intentional self-harm risk. An algorithm based on this finding could enhance clinical assessments support screening, intervention and outreach programs that are at the heart of a Zero Suicide prevention model.
行为健康门诊患者有自我伤害的风险。识别个体或风险因素组合可以区分那些自我伤害风险较高的人。
研究人群(N=248491)包括 2015 年 11 月 1 日至 2016 年 11 月 1 日期间在纽约州医疗补助计划下登记的年龄在 10 至 64 岁之间的有心理健康诊所服务的个人。自我伤害事件是使用急诊和住院就诊的 ICD-10 代码定义的。多预测因素逻辑回归模型适用于数据的子样本,并根据区分性能(曲线下面积或 AUC)与测试样本进行比较。
在 N=248491 名患者中,有 4224 名(1.70%)发生了故意自我伤害事件。与自我伤害风险增加相关的因素包括 17-25 岁、女性以及最近被诊断为抑郁症(AOR=4.3,95%CI:3.6-5.0)、人格障碍(AOR=4.2,95%CI:2.9-6.1)或物质使用障碍(AOR=3.4,95%CI:2.7-4.3)。在索引日期前 90 天内包含人口统计学和新的精神科诊断的多预测因素逻辑回归模型在测试样本上具有良好的区分能力,并且优于竞争模型(AUC=0.86,95%CI:0.85-0.87)。
纽约州医疗补助数据可能不适用于整个美国人口。ICD-10 代码无法区分有意和无意的自我伤害。
我们的结果强调了新的精神科诊断的近期情况在预测有意自我伤害风险的程度和时间方面的有用性。基于这一发现的算法可以增强临床评估,支持筛查、干预和外联计划,这些计划是零自杀预防模型的核心。