[Analysis on serotype and antimicrobial resistance of invasive non-typhoidal ].

To investigate the serotypes and antimicrobial resistance of seven invasive non-typhoidal (iNTS) isolates. For 7 iNTS strains collected, serotype identification, antimicrobial susceptibility testing and whole genome sequencing were performed. We identified, annotated and analyzed the serotypes, MLST types, and antimicrobial resistance genes. Among the 7 tested iNTS isolates, we found one Typhimurium strain and two Ⅰ 4, [5], 12: i:- strains whose MLST types were ST34, two Enteritidis strains, one Corvallis strain and one strain of unknown serotype with the antigenic formulae of Ⅰ 4, [5], 12: d:- (ST279 type). Six of seven strains were monophasic and the deletion or pseudogenization of Flagellum gene might contribute to the enhancement of invasiveness. None was found to be resistant to tigarcycline, aztreonam, amikacin, cephalosporins and carbapenem and one Typhimurium strain was found to be co-resistant to eight classes of antimicrobials at the same time. Resistance genes were generally in accord with relative resistant phenotypes. The iNTS strains could show high level multi-drug resistance, indicating that close attention should be paid to the resistance of iNTS though the overall resistance might be relatively not high.