Ge W X, Tan W L, Teng H Y, Shen H, Han D, Xiao Y, Yin J Y, Hu J
School of Public Health, Soochow University, Suzhou 215006, China.
School of Public Health, Soochow University, Suzhou 215006, China Suzhou Municipal Health Commission, Suzhou 215000, China.
Zhonghua Liu Xing Bing Xue Za Zhi. 2021 Oct 10;42(10):1809-1816. doi: 10.3760/cma.j.cn112338-20201130-01365.
To identify age and gender standardized body mass index among children and adolescents and explore their associations with high blood pressure (HBP) in late adolescence. The current study was based on the Health Promotion Program for Children and Adolescents, school-based surveillance successively conducted from 2012 to 2019 in Suzhou, China. A total of 11 812 children and adolescents aged 16-18 years, who had ≥4 examination records during 2012-2018 and were also involved in a surveillance program in 2019, were included. Latent class growth mixture modeling was used to identify the BMI-Z trajectories in different genders, and multivariate logistic regression was used to analyze the associations between different BMI-Z trajectories and risk of HBP in late adolescence. Six distinct BMI-Z trajectories were determined for both genders:thin, slightly thin,standard, declining, overweight, and obese. Compared with the regular group, the obesity group had 94.0% (=1.94, 95%: 1.43-2.63) and 107.0% (=2.07, 95%: 1.33-3.22) increased risk of developing HBP in late adolescence in boys and girls, respectively. However, a neutral association was found between the descending group and HBP in late adolescence. Persistent obesity in children may increase the risk of HBP in their late adolescence. If an obese child restores normal weight before late adolescence, the risk of HBP may reduce.
确定儿童和青少年中按年龄和性别标准化的体重指数，并探讨其与青春期后期高血压（HBP）的关联。本研究基于中国苏州2012年至2019年连续开展的以学校为基础的儿童和青少年健康促进项目监测。纳入了11812名16 - 18岁的儿童和青少年，他们在2012 - 2018年期间有≥4次检查记录，并且在2019年也参与了监测项目。采用潜在类别增长混合模型确定不同性别的BMI-Z轨迹，并使用多变量逻辑回归分析不同BMI-Z轨迹与青春期后期HBP风险之间的关联。确定了男女共六种不同的BMI-Z轨迹：瘦、稍瘦、标准、下降、超重和肥胖。与正常组相比，肥胖组男孩和女孩在青春期后期患HBP的风险分别增加了94.0%（=1.94，95%：1.43 - 2.63）和107.0%（=2.07，95%：1.33 - 3.22）。然而，下降组与青春期后期的HBP之间存在中性关联。儿童期持续肥胖可能会增加其青春期后期患HBP的风险。如果肥胖儿童在青春期后期之前恢复正常体重，HBP风险可能会降低。
