Shin J Y, Chun J Y, Chang S C, Roh S-G, Lee N-H
Department of Plastic and Reconstructive Surgery, Medical School of Jeonbuk National University, Jeonju, Republic of Korea; Research Institute of Clinical Medicine of Jeonbuk National University-Biomedical Research Institute of Jeonbuk National University Hospital, Jeonju, Republic of Korea.
Department of Plastic and Reconstructive Surgery, Medical School of Jeonbuk National University, Jeonju, Republic of Korea; Research Institute of Clinical Medicine of Jeonbuk National University-Biomedical Research Institute of Jeonbuk National University Hospital, Jeonju, Republic of Korea.
Br J Oral Maxillofac Surg. 2022 Feb;60(2):128-133. doi: 10.1016/j.bjoms.2021.03.007. Epub 2021 Mar 24.
Controversy exists regarding the influence of the graft placement site in the mandible on the success of non-vascularised bone grafts. In this study, we examine the association between the compartment of the mandibular defect and the bone graft failure rate. A systematic literature review and meta-analysis was performed using MEDLINE, Embase, and Cochrane databases. Failure rates according to the compartment of mandibular defect were extracted and analysed by meta-analysis. The Newcastle-Ottawa Scale was used to assess the quality of the studies, and publication bias was evaluated using funnel plots. The search strategy identified 27 publications. After screening, five were selected for review. Based on the result of comparison among these five, we found no significant statistical association between the bone graft failure rate and compartment of mandibular defect, although further investigation of prospective randomised cohort studies is required.
关于下颌骨中移植部位对非血管化骨移植成功的影响存在争议。在本研究中，我们研究了下颌骨缺损区域与骨移植失败率之间的关联。使用MEDLINE、Embase和Cochrane数据库进行了系统的文献综述和荟萃分析。根据下颌骨缺损区域提取失败率，并通过荟萃分析进行分析。采用纽卡斯尔-渥太华量表评估研究质量，并使用漏斗图评估发表偏倚。检索策略确定了27篇出版物。筛选后，选择了5篇进行综述。根据这5篇之间的比较结果，我们发现骨移植失败率与下颌骨缺损区域之间没有显著的统计学关联，尽管需要对前瞻性随机队列研究进行进一步调查。
