采用桡骨前臂游离皮瓣进行下颌骨重建时的骨吸收和愈合率。
Rates of bone reabsorption and union in mandibular reconstruction using the osteocutaneous radial forearm free flap.
作者信息
Karadaghy Omar A, Mussatto Caroline C, Schatz Benjamin A, Li Jennifer, Norris Taylor W, Nallani Rohit, Shnayder Lisa, Kakarala Kiran, Tsue Terance T, Girod Douglas A, Li Yanming, Koestler Devin C, Villwock Mark R, Harn Nick, Bur Andrés M
机构信息
Department of Otolaryngology - Head and Neck Surgery, University of Kansas Medical Center, Kansas City, Kansas, USA.
University of Kansas School of Medicine, Kansas City, Kansas, USA.
出版信息
Head Neck. 2022 Feb;44(2):420-430. doi: 10.1002/hed.26939. Epub 2021 Nov 24.
BACKGROUND
Historical concerns over bone resorption and malunion of the osteocutaneous radial forearm free flap (OCRFFF) limited its widespread adoption for head and neck reconstruction, despite lack of outcomes data evaluating this notion.
METHODS
A retrospective cohort study was performed including patients 18 years or older who underwent reconstruction of the mandible using an OCRFFF. Linear modeling and logistic regression were used to evaluate the change in bone volume and union over time.
RESULTS
One hundred and twenty-one patients were included in the study. A mixed effects linear model incorporating age, sex, treatment type, and number of bone segments did not demonstrate a significant loss of bone volume over time. A logistic regression model identified lack of adjuvant treatment and time to be significantly associated with complete union.
CONCLUSION
This study supports that the OCRFFF is a stable form of osseus reconstruction for defects of the head and neck.
背景
尽管缺乏评估这一观点的结果数据，但对桡骨前臂骨皮瓣（OCRFFF）骨吸收和骨不连的历史担忧限制了其在头颈部重建中的广泛应用。
方法
进行了一项回顾性队列研究，纳入了18岁及以上使用OCRFFF进行下颌骨重建的患者。采用线性建模和逻辑回归来评估骨体积随时间的变化以及骨愈合情况。
结果
该研究共纳入121例患者。纳入年龄、性别、治疗类型和骨段数量的混合效应线性模型未显示骨体积随时间有显著损失。逻辑回归模型确定辅助治疗的缺乏和时间与完全愈合显著相关。
结论
本研究支持OCRFFF是头颈部缺损稳定的骨重建形式。
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