Department of Preventive and Community Medicine, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran.
Guilan Road Trauma Research Center, Guilan University of Medical Sciences, Rasht, Iran.
Arch Iran Med. 2021 Oct 1;24(10):765-770. doi: 10.34172/aim.2021.113.
Hepatitis C is a major cause of liver failure and liver transplantation. The known risk factors of this disease include blood transfusion, injection drug use, high risk sexual behaviors, tattoos, and use of shared blades and syringes. Due to the higher risk of viral hepatitis among people in prison, this study was done to find the seroprevalence of hepatitis C virus (HCV) and associated risk factors in Lakan Prison in Rasht.
Prisoners in Lakan Prison underwent a cross-sectional study in 2018. A questionnaire containing demographic information and risk factors was distributed to the inmates and they were asked complete them. High-risk individuals were selected and a blood sample was taken and tested. Data were collected and analyzed by SPSS18 software.
Out of 2215 prisoners, 1238 people had at least one risk factor, of whom 408 individuals were selected by random sampling. One hundred inmates were positive for anti-HCV antibody, yielding a prevalence of 24.5% (95% CI: 20.4%-28.7%) of whom 42.6% were people who injected drugs and 4 cases were found positive for the hepatitis B surface antigen, yielding a 1% prevalence (95% CI, 0.2%-2%.). A history of injecting drug use (OR 4.28, 95% CI: 2.55-7.17), and previous history of imprisonment (OR 2.94, 95% CI: 1.34-6.53) had association with HCV infection.
The present study shows that hepatitis C is prevalent in prisons and preventive and screening programs should be implemented with necessary training for inmates.
丙型肝炎是肝衰竭和肝移植的主要原因。该病的已知危险因素包括输血、注射吸毒、高危性行为、纹身、使用共享刀片和注射器。由于监狱中的人患病毒性肝炎的风险较高，因此进行了这项研究，以确定拉什特的拉坎监狱中丙型肝炎病毒（HCV）的血清流行率及其相关危险因素。
2018 年，拉坎监狱的囚犯进行了横断面研究。向囚犯分发了一份包含人口统计学信息和危险因素的问卷，并要求他们完成。选择高危个体，抽取血样并进行检测。使用 SPSS18 软件收集和分析数据。
在 2215 名囚犯中，有 1238 人至少有一个危险因素，其中 408 人通过随机抽样选择。有 100 名囚犯抗 HCV 抗体阳性，患病率为 24.5%（95%CI：20.4%-28.7%），其中 42.6%是注射吸毒者，4 例乙型肝炎表面抗原阳性，患病率为 1%（95%CI，0.2%-2%）。有注射吸毒史（OR 4.28，95%CI：2.55-7.17）和既往监禁史（OR 2.94，95%CI：1.34-6.53）与 HCV 感染相关。
本研究表明，丙型肝炎在监狱中流行，应实施预防和筛查计划，并对囚犯进行必要的培训。
