Cossette Benoit, Ricard Geneviève, Poirier Rolande, Gosselin Suzanne, Langlois Marie-France, Imbeault Philippe, Breton Mylaine, Couturier Yves, Sirois Caroline, Lessard-Beaudoin Mélissa, Rodrigue Claudie, Teasdale Julie, Turcotte Jean-Philippe, Mallet Louise
Faculty of Medicine and Health Sciences, University of Sherbrooke, Sherbrooke, Canada.
Research Centre on Aging, Integrated University Health and Social Services Centre of Estrie, Sherbrooke, Canada.
J Am Geriatr Soc. 2022 Mar;70(3):766-776. doi: 10.1111/jgs.17575. Epub 2021 Nov 24.
Pharmacist-led transitions of care (TOC) interventions have been described as some of the most promising interventions to reduce medication-related harm (MRH) in older adults. This study analyzed the feasibility of pharmacist-led TOC interventions between hospitals, multidisciplinary primary care clinics (PCC), and community pharmacies.
Adults aged 65 years and older at risk of MRH in three regions of Quebec, Canada, with contrasting contexts of care based on university affiliation were recruited in this multicenter, single arm, and prospective intervention cohort. The hospital pharmacist developed the pharmaceutical care plan in collaboration with the hospital physician and transferred this plan with the hospitalization summary, at hospital discharge, to the PCC family physician and to the community and PCC pharmacists. A consultation with the community pharmacist was scheduled within seven days of hospital discharge and with the PCC pharmacist when appropriate. Feasibility outcomes included the time to complete the interventions and their location.
The 123 eligible patients had a mean age of 78.5 years, and 63.4% were females. The most frequent inclusion criterion was 10 medications or more, including one high-risk medication for 90 patients (73%). Recruitment in one region was stopped after three months due to unsuccessful recruitment of key PCC. The hospital pharmacist interventions took a median of 165 min. The first consultations of the PCC and community pharmacists took a median of 15 and 50 min. Among the 96 patients with a post-discharge pharmacist follow-up, 23 (24.0%) had a consultation with a PCC pharmacist, with 65.2% of the consultations conducted at the PCC. The community pharmacists conducted a consultation with 88 patients (93%), with more than 70% of consultations conducted by phone.
Our study showed the feasibility of pharmacist-led TOC interventions between hospitals, PCC, and community pharmacies and detailed the novel role that PCC pharmacists played in optimizing TOC interventions.
由药剂师主导的照护过渡(TOC)干预措施被认为是减少老年人药物相关伤害(MRH)最具前景的干预措施之一。本研究分析了由药剂师主导的在医院、多学科初级保健诊所(PCC)和社区药房之间进行TOC干预的可行性。
在加拿大魁北克三个地区招募65岁及以上有MRH风险的成年人,这些地区基于大学附属关系具有不同的照护背景。本研究为多中心、单臂、前瞻性干预队列研究。医院药剂师与医院医生合作制定药物治疗护理计划,并在患者出院时将该计划连同住院总结一起转交给PCC家庭医生以及社区和PCC药剂师。出院后7天内安排与社区药剂师进行会诊,并在适当的时候与PCC药剂师进行会诊。可行性结果包括完成干预的时间及其地点。
123名符合条件的患者平均年龄为78.5岁,63.4%为女性。最常见的纳入标准是服用10种或更多药物,其中90名患者(73%)服用一种高风险药物。由于关键PCC招募不成功,三个月后停止了在一个地区的招募。医院药剂师的干预时间中位数为165分钟。PCC和社区药剂师的首次会诊时间中位数分别为15分钟和50分钟。在96名出院后有药剂师随访的患者中,23名(24.0%)与PCC药剂师进行了会诊,其中65.2%的会诊在PCC进行。社区药剂师与88名患者(93%)进行了会诊,超过70%的会诊通过电话进行。
我们的研究表明了由药剂师主导的在医院、PCC和社区药房之间进行TOC干预的可行性,并详细阐述了PCC药剂师在优化TOC干预中所发挥的新作用。