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Polyurethane foam dressings ameliorating local adverse effects of azacitidine: a randomized controlled trial.

作者信息

Wang Yufang, Chen Chunrong, Lin Yanfang, Chen Meihua, Cai Jinxiang, Chen Xiujuan, Chen Saizhen, Huang Xiaomei, Lin Yanjuan

机构信息

Fujian Institute of Hematology, Fujian Provincial Key Laboratory on Hematology, Fujian Medical University Union Hospital, Fuzhou City, China.

Department of Nursing, Fujian Medical University Union Hospital, Fuzhou City, China.

出版信息

Leuk Lymphoma. 2022 Mar;63(3):703-709. doi: 10.1080/10428194.2021.1998482. Epub 2021 Nov 25.

DOI:10.1080/10428194.2021.1998482
PMID:34818966
Abstract

This study investigated the use of polyurethane foam dressings to prevent local adverse reactions of subcutaneous azacitidine injection. Patients receiving a subcutaneous azacitidine injection were randomly divided into experimental and control groups. A total of 55 patients were included in each group. A polyurethane foam dressing was used to cover the injection site of patients in the experimental group. Conventional treatment was used in the control group. Injection site pain and local skin reactions were assessed after the intervention in both groups. The score and duration of pain, the incidence and duration of local skin adverse reactions, and the incidence of severe reactions in the experimental group were significantly lower than in the control group ( < 0.05). Polyurethane foam dressing can effectively reduce local adverse reactions of subcutaneous injection of azacitidine, relieve pain, shorten the duration of local pain and adverse reactions, and improve the quality of nursing.

摘要

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