Tipsing Worakan, Sawanyawisuth Kittisak
Srinakharinwirot University, Bangkok, Thailand.
Khon Kaen University, Khon Kaen, Thailand.
Reumatologia. 2021;59(5):309-312. doi: 10.5114/reum.2021.110611. Epub 2021 Nov 7.
Rheumatoid arthritis (RA) is a chronic inflammatory arthritis that may lead to severe joint pain. There are several scores to evaluate the disease activity of RA. This study aimed to evaluate if clinical factors which representing activity scores and health assessment score.
This study was conducted prospectively by including adult patients with RA. Clinical factors and 5 RA disease activity and health assessment scores were evaluated. Each activity score was executed for clinical predictors by using multivariate linear regression analysis.
There were 33 female adult patients in the study. The average (SD) age was 52.33 (11.11) years, while the duration of RA was 7.65 years. The DAS28 ESR had 1 predictor: RA duration with a coefficient of -0.04. For DAS28 CRP, CDAI, and SDAI scores, body mass index (BMI) and RA duration were independent factors for the scores with negative coefficient values. For the HAQ score, both age and rheumatoid duration were positively associated with the score. The coefficients of both factors were 0.02 and 0.03, respectively.
Age, RA duration, and BMI were associated with RA activity and functional score. Body mass index is a potential modifiable factor that may be associated with RA activities.
类风湿性关节炎（RA）是一种慢性炎症性关节炎，可能导致严重的关节疼痛。有多种评分用于评估RA的疾病活动度。本研究旨在评估代表活动评分和健康评估评分的临床因素。
本研究前瞻性纳入成年RA患者。评估临床因素以及5种RA疾病活动度和健康评估评分。通过多元线性回归分析对每个活动评分进行临床预测因素分析。
本研究中有33名成年女性患者。平均（标准差）年龄为52.33（11.11）岁，RA病程为7.65年。DAS28 ESR有1个预测因素：RA病程，系数为-0.04。对于DAS28 CRP、CDAI和SDAI评分，体重指数（BMI）和RA病程是评分的独立因素，系数为负值。对于HAQ评分，年龄和类风湿病程均与评分呈正相关。这两个因素的系数分别为0.02和0.03。
年龄、RA病程和BMI与RA活动度及功能评分相关。体重指数是一个可能与RA活动相关的潜在可改变因素。
