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早期复极与冠状动脉疾病的严重程度:一项病例对照研究。

Early repolarization and the severity of coronary artery disease: A case-control study.

作者信息

Hemmati Roholla, Mohsenzadeh Yousef, Salaminia Shirvan, Sayehmiri Fatemeh

机构信息

Department of Cardiology, School of Medicine, Ilam University of Medical Sciences, Ilam, Iran.

Department of Cardiac Surgery, Yasuj University of Medical Science, Yasuj, Iran.

出版信息

Caspian J Intern Med. 2021 Fall;12(4):526-532. doi: 10.22088/cjim.12.4.526.

DOI:10.22088/cjim.12.4.526
PMID:34820058
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8590411/
Abstract

BACKGROUND

Early repolarization (ER) is a common finding of the routine electrocardiogram (ECG). The ER usually considered a benign ECG finding, nevertheless a controversy. This study was conducted to investigate the relationship between early repolarization (ER) and the severity of coronary artery disease in patients with a diagnostic coronary angiography.

METHODS

This case-control study included ninety patients (45 patients and 45 control groups) with a diagnostic angiography and was conducted in 2015. After obtaining informed consent, patients with angiography for ER were considered as cases and those for other purposes were as controls. Data were analyzed using SPSS software Version 16. A p-value lesser than 0.05 was significant.

RESULTS

The frequency of ER was higher in men (75.6%), and there was a significant relationship between sex and ER (P=0.003). The mean age of the patients in the ER group was lower than that of non-ER patients, but not statistically significant (P=0.1). Abnormal angiography was more prevalent in patients with ER than non-ER patients (59.6% vs. 40.4%). ER morphology showed a significant correlation to abnormal angiography and also stenosis severity (P=0.035).

CONCLUSION

ER was higher in men than in women. There was a significant correlation between the existence of ER morphology and atherosclerosis severity. Screening programs for ER detection may reduce the risk of arrhythmias and prevent related complications.

摘要

背景

早期复极(ER)是常规心电图(ECG)常见表现。ER通常被认为是一种良性心电图表现,但仍存在争议。本研究旨在探讨诊断性冠状动脉造影患者中早期复极(ER)与冠状动脉疾病严重程度之间的关系。

方法

本病例对照研究纳入了90例接受诊断性血管造影的患者(45例患者和45例对照组),研究于2015年进行。在获得知情同意后,因ER进行血管造影的患者被视为病例组,因其他目的进行血管造影的患者为对照组。使用SPSS 16.0软件进行数据分析。p值小于0.05具有统计学意义。

结果

男性ER发生率较高(75.6%),性别与ER之间存在显著关系(P = 0.003)。ER组患者的平均年龄低于非ER患者,但差异无统计学意义(P = 0.1)。ER患者中异常血管造影比非ER患者更常见(59.6%对40.4%)。ER形态与异常血管造影以及狭窄严重程度显著相关(P = 0.035)。

结论

男性ER发生率高于女性。ER形态的存在与动脉粥样硬化严重程度之间存在显著相关性。ER检测筛查项目可能会降低心律失常风险并预防相关并发症。

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Prevalence of Early Repolarization Patterns in Adults.成人早期复极模式的患病率。
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Early repolarization is associated with significant coronary artery stenosis in asymptomatic adults.早期复极与无症状成年人的显著冠状动脉狭窄有关。
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Benign clinical significance of J-wave pattern (early repolarization) in highly trained athletes.训练有素的运动员中J波形态(早期复极)的良性临床意义。
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