Li Yajie, Zhang Hang, Wang Zhenwei, Shi Hongbin, Nie Lihong, Zhao Ruining
Department of Urology, General Hospital of Ningxia Medical University, Yinchuan, Ningxia, 750004, PR China.
Department of Surgery, Bazhong Central Hospital, Bazhong, Sichuan, 636000, PR China.
Urol Case Rep. 2021 Nov 8;40:101931. doi: 10.1016/j.eucr.2021.101931. eCollection 2022 Jan.
One patient with bladder leiomyosarcoma and urothelial carcinoma is very rare. Only 10 cases have been reported in the literature. A 70-year-old patient was admitted due to bladder tumor. Two TURBTs were performed confirming the patient was free of tumor, and pathology reported low-grade urothelial carcinoma. Three years later, a tumor was also found on the right anterolateral wall of urinary bladder and was diagnosed as leiomyosarcoma by pathological examination. Radical cystectomy was performed. With 45 months follow-up, the patient has no recurrence. Two malignancies in the same anatomic region at different time has never been reported to date.
一名患有膀胱平滑肌肉瘤和尿路上皮癌的患者极为罕见。文献中仅报道过10例。一名70岁患者因膀胱肿瘤入院。进行了两次经尿道膀胱肿瘤切除术，确认患者无肿瘤残留，病理报告为低级别尿路上皮癌。三年后，在膀胱右前外侧壁也发现了一个肿瘤，经病理检查诊断为平滑肌肉瘤。遂行根治性膀胱切除术。经过45个月的随访，患者未出现复发。同一解剖区域在不同时间出现两种恶性肿瘤的情况迄今从未有过报道。
