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诊断实验室中基于液相色谱-串联质谱（LC-MS/MS）分析系列验证的建议标准。

A suggested standard for validation of LC-MS/MS based analytical series in diagnostic laboratories.

作者信息

Vogeser Michael, Stone Judith A

机构信息

Hospital of the University of Munich (LMU), Institute of Laboratory Medicine, Munich, Germany.

University of California, San Francisco Medical Center, Laboratory Medicine, Parnassus Chemistry, San Francisco, CA, USA.

出版信息

Clin Mass Spectrom. 2020 Feb 28;16:25-32. doi: 10.1016/j.clinms.2020.02.002. eCollection 2020 Apr.

DOI:10.1016/j.clinms.2020.02.002
PMID:34820517
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8600988/
Abstract

•Policies applied to confirm LC-MS/MS-based results differ between laboratories.•We suggest a systematic approach for validation of individual diagnostic series.•An individual series validation plan can be established with a checklist.

摘要

•各实验室用于确认基于液相色谱-串联质谱（LC-MS/MS）结果的政策有所不同。

•我们建议采用系统方法对单个诊断系列进行验证。

•可以通过清单制定单个系列验证计划。

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Comparison of four clinically validated testosterone LC-MS/MS assays: Harmonization is an attainable goal.四种经临床验证的睾酮液相色谱-串联质谱检测方法的比较：实现标准化是一个可达成的目标。
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Skyline Performs as Well as Vendor Software in the Quantitative Analysis of Serum 25-Hydroxy Vitamin D and Vitamin D Binding Globulin.在血清25-羟基维生素D和维生素D结合球蛋白的定量分析中，Skyline与供应商软件的性能相当。
Clin Chem. 2018 Feb;64(2):408-410. doi: 10.1373/clinchem.2017.282293. Epub 2017 Dec 4.
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Quality management in clinical application of mass spectrometry measurement systems.质谱测量系统临床应用中的质量管理
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