诊断实验室中基于液相色谱-串联质谱（LC-MS/MS）分析系列验证的建议标准。
A suggested standard for validation of LC-MS/MS based analytical series in diagnostic laboratories.
作者信息
Vogeser Michael, Stone Judith A
机构信息
Hospital of the University of Munich (LMU), Institute of Laboratory Medicine, Munich, Germany.
University of California, San Francisco Medical Center, Laboratory Medicine, Parnassus Chemistry, San Francisco, CA, USA.
出版信息
Clin Mass Spectrom. 2020 Feb 28;16:25-32. doi: 10.1016/j.clinms.2020.02.002. eCollection 2020 Apr.
Abstract
•Policies applied to confirm LC-MS/MS-based results differ between laboratories.•We suggest a systematic approach for validation of individual diagnostic series.•An individual series validation plan can be established with a checklist.
摘要
•各实验室用于确认基于液相色谱-串联质谱（LC-MS/MS）结果的政策有所不同。
•我们建议采用系统方法对单个诊断系列进行验证。
•可以通过清单制定单个系列验证计划。
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