Pineda Celis A, Valle Farías J L, Juárez Aragón G, Games Eternod J, Serafín F J
Bol Med Hosp Infant Mex. 1978 Jul-Aug;35(4):599-607.
Fourteen children admitted to the Hospital de Pediatría of the C.M.N. of the I.M.S.S. with the diagnosis of acute infectious laryngotracheobronchitis were divided into two groups with similar conditions for their study. The benefit derived from the application of recemic epinephrine with intermittent positive pressure was confirmed 15 and 30 minutes later by means of a double blind study; the improvement was swift and spectacular, but temporary; therefore, such treatment must be given only in hospitals, since relapses may show up two to four hours later, making in dangerous to send the patients home or to apply to ambulatory cases. The use of racemic epinephrine is proposed for hospitals having equipment and personnel trained in its management and the convenience of further studies is set forth to determine the period of effectiveness of racemic epinephrine and the advantage of giving repeated doses.
14名被墨西哥社会保障局国家儿童医学中心儿科医院收治，诊断为急性感染性喉气管支气管炎的儿童被分为两组，两组情况相似用于研究。通过双盲研究证实，应用消旋肾上腺素并间歇正压通气后15分钟和30分钟时的效果；改善迅速且显著，但为暂时性；因此，这种治疗必须仅在医院进行，因为两到四小时后可能会出现复发，将患者送回家或应用于门诊病例会很危险。建议有设备和经过管理培训人员的医院使用消旋肾上腺素，并提出进行进一步研究以确定消旋肾上腺素的有效期限以及重复给药的优势。
