慢性肾脏病与膳食补充：对炎症和氧化应激的影响
Chronic Kidney Disease and Dietary Supplementation: Effects on Inflammation and Oxidative Stress.
作者信息
Martello Elisa, Perondi Francesca, Bruni Natascia, Bisanzio Donal, Meineri Giorgia, Lippi Ilaria
机构信息
Division of Epidemiology and Public Health, School of Medicine, University of Nottingham, Nottingham NG5 1PB, UK.
Department of Veterinary Science, University of Pisa, San Piero a Grado (PI), 56124 Pisa, Italy.
出版信息
Vet Sci. 2021 Nov 15;8(11):277. doi: 10.3390/vetsci8110277.
Chronic kidney disease (CKD) causes an irreversible loss of kidney functioning in dogs. This double-blind case-control study evaluates the efficacy of a dietary supplement, which contains calcium carbonate, calcium lactate-gluconate, chitosan, sodium bicarbonate, Lactobacillus acidophilus D2/CSL, L. extract, and fructooligosaccharides, in dogs in advanced CKD stage. Thirty dogs were enrolled in the study; half were administered the new dietary supplementation for 90 days, while the others were used as controls. Hematologic, biochemical, and urinalysis were performed. This novel dietary supplement mainly reported a good control of uremia, phosphate, acid-base balance, blood pressure, inflammation, and oxidative stress in dogs with advanced stages of CKD.
慢性肾病（CKD）会导致犬类肾脏功能不可逆转的丧失。这项双盲病例对照研究评估了一种膳食补充剂在晚期CKD阶段犬类中的功效，该补充剂含有碳酸钙、乳酸葡萄糖酸钙、壳聚糖、碳酸氢钠、嗜酸乳杆菌D2/CSL、L.提取物和低聚果糖。30只犬参与了该研究；其中一半接受新的膳食补充剂治疗90天，另一半用作对照。进行了血液学、生化和尿液分析。这种新型膳食补充剂主要显示出对晚期CKD犬类的尿毒症、磷酸盐、酸碱平衡、血压、炎症和氧化应激有良好的控制作用。
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