Suppr超能文献

史蒂文斯-约翰逊综合征相关牙齿异常的诊断与治疗方法:一例报告

Diagnostic and Treatment Approach in the Management of Dental Anomalies Associated with Stevens-Johnson Syndrome: A Case Report.

作者信息

Katyal Sakshi, Yadav Vijay

机构信息

Division of Orthodontics and Dentofacial Deformities, Centre for Dental Education and Research, All India Institute of Medical Sciences, New Delhi, India.

Division of Conservative Dentistry and Endodontics, Center for Dental Education and Research, All India Institute of Medical Sciences, New Delhi, India.

出版信息

Int J Clin Pediatr Dent. 2021 Jul-Aug;14(4):569-574. doi: 10.5005/jp-journals-10005-1986.

Abstract

BACKGROUND

Stevens-Johnson syndrome is a rare medical condition with severe mucocutaneous lesions due to adverse drug reactions characterized by exudative multiform erythema, stomatitis, and conjunctivitis. Long-term oral consequences of such cases include xerostomia, caries, impactions, and multiple dental developmental aberrations as short root anomalies.

AIM AND OBJECTIVE

To highlight the role of pedodontist in early diagnosis and treatment planning of dental abnormalities due to Stevens-Johnson syndrome (SJS) using a cone-beam computed tomography (CBCT).

CASE DESCRIPTION

A 16-year-old male reported a chief complaint of decayed posterior teeth. Past medical history revealed adverse reactions to an unknown drug at the age of 4 to 5 years. In addition to carious teeth, clinical examination revealed that all canines were missing along with mandibular incisors. On CBCT examination, abnormal short, plump roots with normal crown were seen in all permanent first molars and incisors along with impacted canines and mandibular incisors. This condition was diagnosed as a "Short root anomaly" (SRA) due to SJS. He was found positive to allergy tests for NSAIDs such as ibuprofen and paracetamol.

CONCLUSION

NSAIDs can cause a severe adverse reaction resulting in SJS. If this hypersensitivity reaction occurs early during the development of a permanent tooth it may cause dental anomalies such as short roots, root dysmorphia, agenesis, and multiple impacted teeth.

CLINICAL SIGNIFICANCE

This report highlights a unique case of multiple dental aberrations due to SJS and the role of a pedodontist in the early diagnosis and treatment planning of such cases with the help of CBCT. Short root anomalies can be misdiagnosed as root resorption or immature apex. Medical history, clinical and CBCT findings are essential for diagnosis and treatment in SJS patients. Careful orthodontic treatment planning is required in cases of short root anomalies.

HOW TO CITE THIS ARTICLE

Katyal S, Yadav V. Diagnostic and Treatment Approach in the Management of Dental Anomalies Associated with Stevens-Johnson Syndrome: A Case Report. Int J Clin Pediatr Dent 2021;14(4):569-574.

摘要

背景

史蒂文斯-约翰逊综合征是一种罕见的医学病症,因药物不良反应导致严重的黏膜皮肤损伤,其特征为渗出性多形红斑、口腔炎和结膜炎。此类病例的长期口腔后果包括口干、龋齿、阻生以及多种牙齿发育异常,如短根畸形。

目的

强调儿童牙医在使用锥形束计算机断层扫描(CBCT)对史蒂文斯-约翰逊综合征(SJS)所致牙齿异常进行早期诊断和治疗计划制定中的作用。

病例描述

一名16岁男性主诉后牙龋坏。既往病史显示其在4至5岁时对一种未知药物有不良反应。除龋齿外,临床检查发现所有尖牙缺失,同时下颌切牙也缺失。CBCT检查显示,所有恒牙第一磨牙和切牙的牙根异常短而粗壮,冠部正常,同时伴有阻生尖牙和下颌切牙。该病症被诊断为因SJS导致的“短根畸形”(SRA)。对布洛芬和扑热息痛等非甾体抗炎药的过敏试验显示他呈阳性。

结论

非甾体抗炎药可引起严重不良反应,导致SJS。如果这种超敏反应在恒牙发育早期发生,可能会导致牙齿异常,如短根、牙根形态异常、牙胚缺失和多个牙齿阻生。

临床意义

本报告突出了一例因SJS导致的多种牙齿畸形的独特病例,以及儿童牙医借助CBCT在此类病例早期诊断和治疗计划制定中的作用。短根畸形可能被误诊为牙根吸收或根尖未发育成熟。病史、临床和CBCT检查结果对于SJS患者的诊断和治疗至关重要。对于短根畸形病例,需要进行仔细的正畸治疗计划制定。

如何引用本文

Katyal S, Yadav V. 诊断与治疗方法在史蒂文斯 - 约翰逊综合征相关牙齿异常管理中的应用:一例报告。《国际临床儿科牙科学杂志》2021年;14(4):569 - 574。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验