Department of Cardiovascular Medicine, Matsumoto Kyoritsu Hospital, 9-26 Habaue, Matsumoto City, Nagano, 390-8505, Japan.
J Interv Card Electrophysiol. 2022 Apr;63(3):651-659. doi: 10.1007/s10840-021-01095-8. Epub 2021 Nov 26.
Cardiac implantable electronic devices (CIEDs) offer diagnostic information such as device-measured physical activity (PA). Peak oxygen consumption (VO) measured by cardiopulmonary exercise testing (CPET) is the most objective variable showing exercise capacity. The purpose of this study was to investigate the relationship between these 2 variables.
We retrospectively studied consecutive patients with CIEDs undergoing CPET between April 1, 2018, and January 31, 2021. These patients were divided into 2 groups: patients with peak VO ≤ 14 ml/kg/min (low peak VO group) and those showing peak VO > 14 ml/kg/min (high peak VO group). The peak device-measured PA was compared between the 2 groups. The relationship between the peak device-measured PA and peak VO was also investigated.
There were 50 and 51 patients in the low and high peak VO groups, respectively. The peak device-measured PA, which was expressed in units of hours/day, was significantly lower in the low peak VO group than in the high peak VO group (3.06, interquartile range [2.43-4.00] vs. 5.50, interquartile range [4.04-6.70] p < 0.01). The peak device-measured PA and peak VO showed a significant positive correlation (Spearman's ρ = 0.53; p < 0.01). Furthermore, receiver operating characteristic curve analysis showed that a peak device-measured PA > 3.87 h/day could predict high peak VO (80.4%, sensitivity; 72.0%, specificity). In multivariate linear regression analysis, peak device-measured PA was an independent predictor of peak VO (regression coefficient, 0.61; 95% confidence interval, 0.33-0.89; p < 0.01).
Peak device-measured PA was significantly associated with peak VO.
心脏植入式电子设备（CIEDs）提供设备测量的体力活动（PA）等诊断信息。心肺运动测试（CPET）测量的峰值耗氧量（VO）是最能客观反映运动能力的变量。本研究旨在探讨这两个变量之间的关系。
我们回顾性研究了 2018 年 4 月 1 日至 2021 年 1 月 31 日期间接受 CPET 的连续 CIED 患者。这些患者分为两组：峰值 VO≤14ml/kg/min（低峰值 VO 组）和峰值 VO>14ml/kg/min（高峰值 VO 组）。比较两组的峰值设备测量 PA。还研究了峰值设备测量 PA 与峰值 VO 之间的关系。
低峰值 VO 组和高峰值 VO 组分别有 50 例和 51 例患者。以小时/天为单位表示的峰值设备测量 PA 在低峰值 VO 组明显低于高峰值 VO 组（3.06，四分位距[2.43-4.00] vs. 5.50，四分位距[4.04-6.70]，p<0.01）。峰值设备测量 PA 与峰值 VO 呈显著正相关（Spearman ρ=0.53；p<0.01）。此外，受试者工作特征曲线分析表明，峰值设备测量 PA>3.87h/天可预测高峰值 VO（80.4%，敏感性；72.0%，特异性）。多元线性回归分析显示，峰值设备测量 PA 是峰值 VO 的独立预测因子（回归系数，0.61；95%置信区间，0.33-0.89；p<0.01）。
峰值设备测量 PA 与峰值 VO 显著相关。
