Pearce I, Pearce J M
Br Med J. 1978 May 27;1(6124):1402-4. doi: 10.1136/bmj.1.6124.1402.
A review of the effects of using bromocriptine in Parkinson's disease showed that it rarely helps patients not primarily improved by levodopa. Patients who show late failure with levadopa and whose response to treatment is declining are helped by combining the two drugs. High cost and severe psychosis are the main disadvantages of bromocriptine, and, although it is not recommended for patients who are doing well on levodopa, it is the best available drug for hospital use in patients who show late failure with levodopa.
一项关于使用溴隐亭治疗帕金森病效果的综述表明,对于那些主要未通过左旋多巴得到改善的患者,溴隐亭很少能起到帮助作用。对于左旋多巴出现晚期失效且对治疗反应逐渐下降的患者,联合使用这两种药物会有帮助。高成本和严重的精神病是溴隐亭的主要缺点,虽然不建议在左旋多巴治疗效果良好的患者中使用,但对于左旋多巴出现晚期失效的住院患者来说,它是目前可用的最佳药物。