Li Na, Ma Junxiong, Zhou Shuduo, Dong Xuejie, Maimaitiming Mailikezhati, Jin Yinzi, Zheng Zhijie
Department of Global Health, School of Public Health, Peking University, Beijing 100871, China.
Institute for Global Health and Development, Peking University, Beijing 100871, China.
Healthcare (Basel). 2021 Oct 28;9(11):1462. doi: 10.3390/healthcare9111462.
(1) Background: Chest pain center accreditation has been associated with improved timelines of primary percutaneous coronary intervention (PCI) for ST-segment elevated myocardial infarction (STEMI). However, evidence from low- and middle-income regions was insufficient, and whether the sensitivity to improvements differs between walk-in and emergency medical service (EMS)-transported patients remained unclear. In this study, we aimed to examine the association of chest pain center accreditation status with door-to-balloon (D2B) time and the potential modification effect of arrival mode. (2) Methods: The associations were examined using generalized linear mixed models, and the effect modification of arrival mode was examined by incorporating an interaction term in the models. (3) Results: In 4186 STEMI patients, during and after accreditation were respectively associated with 65% (95% CI: 54%, 73%) and 71% (95% CI: 61%, 79%) reduced risk of D2B time being more than 90 min (using before accreditation as the reference). Decreases of 27.88 (95% CI: 19.57, 36.22) minutes and 26.55 (95% CI: 17.45, 35.70) minutes in D2B were also observed for the during and after accreditation groups, respectively. The impact of accreditation on timeline improvement was greater for EMS-transported patients than for walk-in patients. (4) Conclusions: EMS-transported patients were more sensitive to the shortened in-hospital delay associated with the initiative, which could exacerbate the existing disparity among patients with different arrival modes.
(1) 背景:胸痛中心认证与ST段抬高型心肌梗死(STEMI)患者接受直接经皮冠状动脉介入治疗(PCI)的时间缩短相关。然而,来自低收入和中等收入地区的证据不足,且自行就诊患者与急诊医疗服务(EMS)转运患者对改善措施的敏感性差异仍不明确。在本研究中,我们旨在探讨胸痛中心认证状态与门球时间(D2B)的关联以及就诊方式的潜在修正作用。(2) 方法:采用广义线性混合模型检验关联,并通过在模型中纳入交互项来检验就诊方式的效应修正。(3) 结果:在4186例STEMI患者中,认证期间及认证后D2B时间超过90分钟的风险分别降低65%(95%CI:54%,73%)和71%(95%CI:61%,79%)(以认证前为参照)。认证期间组和认证后组的D2B时间分别减少27.88分钟(95%CI:19.57,36.22)和26.55分钟(95%CI:17.45,35.70)。认证对时间改善的影响在EMS转运患者中比对自行就诊患者更大。(4) 结论:EMS转运患者对与该举措相关的缩短院内延迟更为敏感,这可能会加剧不同就诊方式患者之间现有的差异。