Boerner Thomas, Piso Pompiliu
Memorial Sloan Kettering Cancer Center, Department of Surgery, 1275 York Avenue, New York, NY 10065, USA.
Department of Surgery, Krankenhaus Barmherzige Brüder Regensburg, Prüfeninger Straße 86, 93049 Regensburg, Germany.
J Clin Med. 2021 Nov 12;10(22):5263. doi: 10.3390/jcm10225263.
Due to limited systemic treatment options, peritoneal carcinomatosis of gastric origin is still associated with a dismal outcome and is claimed a terminal disease. In the past, surgery had not been considered as a potential treatment option. However, there is emerging evidence that in selected patients, locoregional treatment modalities including cytoreductive surgery of peritoneal carcinomatosis can improve survival in patients with gastric cancer. These operative procedures are complex and challenging, and a high surgical expertise of the treating physician is necessary to prevent major postoperative morbidity and mortality with a delay of further systemic therapy. This review summarizes our current knowledge and personal experience regarding the techniques of cytoreductive surgery for peritoneal metastasis of gastric origin.
由于全身治疗选择有限，胃源性腹膜癌病的预后仍然很差，被认为是一种终末期疾病。过去，手术未被视为一种潜在的治疗选择。然而，越来越多的证据表明，在特定患者中，包括腹膜癌病细胞减灭术在内的局部区域治疗方式可改善胃癌患者的生存率。这些手术操作复杂且具有挑战性，治疗医师需要具备高超的外科专业知识，以防止术后出现严重并发症和死亡，并避免进一步全身治疗的延迟。本综述总结了我们目前关于胃源性腹膜转移癌细胞减灭术技术的知识和个人经验。
