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用于数字微流控调制的液滴通过电极上的小孔传输。

Droplet Transportation through an Orifice on Electrode for Digital Microfluidics Modulations.

作者信息

Chu Ting-Chia, Lu Yen-Wen

机构信息

Department of Biomechatronics Engineering, National Taiwan University, Taipei 10607, Taiwan.

出版信息

Micromachines (Basel). 2021 Nov 12;12(11):1385. doi: 10.3390/mi12111385.

DOI:10.3390/mi12111385
PMID:34832797
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8618053/
Abstract

A digital microfluidic modular interface (chip-to-chip interface) which possesses an electrode with an orifice to vertically transport core-shell droplets is presented. The electrodes were geometrically designed to promote droplet deformation and suspension. The droplets were then applied with an electrical potential for insertion into and passage through the orifice. The concepts were tested with three types of droplets at the volume of 0.751.5 μL, which is usually difficult to transfer through an orifice. The integration of electrowetting on dielectric (EWOD) with paper-based microfluidics was demonstrated: the droplet could be transported within 10 s. More importantly, most of the core droplet (97%) was extracted and passed through with only minimal shell droplets accompanying it.

摘要

本文提出了一种数字微流控模块化接口(芯片到芯片接口),该接口拥有一个带有孔口的电极,用于垂直传输核壳液滴。电极在几何形状上经过设计,以促进液滴变形和悬浮。然后给液滴施加电势,使其插入孔口并通过孔口。这些概念通过三种体积为0.75至1.5μL的液滴进行了测试,这种体积的液滴通常很难通过孔口传输。本文展示了介电层上电润湿(EWOD)与纸基微流控技术的集成:液滴可在10秒内传输。更重要的是,大部分核心液滴(约97%)被提取并通过,仅有极少的壳层液滴伴随。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f1c6/8618053/af9cf37dc327/micromachines-12-01385-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f1c6/8618053/f160b45bd07e/micromachines-12-01385-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f1c6/8618053/f9a316d2a1ec/micromachines-12-01385-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f1c6/8618053/3c84019b5369/micromachines-12-01385-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f1c6/8618053/1ad8e1050b70/micromachines-12-01385-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f1c6/8618053/52ae79d9130d/micromachines-12-01385-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f1c6/8618053/90d7ffa2f581/micromachines-12-01385-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f1c6/8618053/af9cf37dc327/micromachines-12-01385-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f1c6/8618053/f160b45bd07e/micromachines-12-01385-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f1c6/8618053/f9a316d2a1ec/micromachines-12-01385-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f1c6/8618053/3c84019b5369/micromachines-12-01385-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f1c6/8618053/1ad8e1050b70/micromachines-12-01385-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f1c6/8618053/52ae79d9130d/micromachines-12-01385-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f1c6/8618053/90d7ffa2f581/micromachines-12-01385-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f1c6/8618053/af9cf37dc327/micromachines-12-01385-g007.jpg

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3
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Interface Focus. 2017 Dec 6;7(6):20170013. doi: 10.1098/rsfs.2017.0013. Epub 2017 Oct 20.
4
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Biosens Bioelectron. 2016 Mar 15;77:845-52. doi: 10.1016/j.bios.2015.10.036. Epub 2015 Oct 22.
5
Rapid and sensitive detection of antibiotic resistance on a programmable digital microfluidic platform.在可编程数字微流控平台上快速灵敏地检测抗生素耐药性。
Lab Chip. 2015 Jul 21;15(14):3065-75. doi: 10.1039/c5lc00462d.
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Three-dimensional digital microfluidic manipulation of droplets in oil medium.油介质中液滴的三维数字微流控操控
Sci Rep. 2015 Jun 2;5:10685. doi: 10.1038/srep10685.
7
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Lab Chip. 2015 May 21;15(10):2201-12. doi: 10.1039/c5lc00014a.
8
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9
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10
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