Cardiothoracic Pathology Department, University of Medicine and Pharmacy Carol Davila, 020021 Bucharest, Romania.
Department of Cardiology, Elias Emergency University Hospital, 011461 Bucharest, Romania.
Medicina (Kaunas). 2021 Oct 20;57(11):1139. doi: 10.3390/medicina57111139.
Atrial fibrillation recurrences (AFR) after radiofrequency catheter ablation (RFCA) are not uncommon, up to 65% of patients having relapses in the first year. However, current data are based mainly on studies from centres with a large volume of ablations, as they include technically inhomogeneous interventions, and populations with different types of AF. The aim of our study was to assess and stratify the risk at 6 and 12 months for AFR after a single RFCA, in patients with paroxysmal AF, in a centre with low volume activity. We enrolled 40 patients who underwent an initial RFCA, followed by continuous 48 h ECG monitoring at 1, 3, 6, and 12 months. Patients self-monitored their cardiac activity by random daily radial pulse palpation or in the presence of palpitations. Ten independent predictors for late AFR were identified, and a 6-month risk score was computed using three of them: AFR duration in the first month, number of AFR between 1 and 3 months, and supraventricular ectopics per 24 h at 6 months. The score can explain 59% of the AFR ( = 0.001). A further 12-month assessment identified three independent predictors. The presence of AFR between 6-12 months is the most important of them (OR = 23.11, 95% CI = 3.87-137.83, = 0.001), explaining 45% of AFR over 1 year. The risk scores at 6 and 12 months were internally validated. The 6-month score proved to be a useful tool in guiding further strategy for patients with a low risk, while a longer follow-up to 12 months may avoid unnecessary early reinterventions.
心房颤动(AF)射频导管消融(RFCA)后复发并不少见,多达 65%的患者在第一年复发。然而,目前的数据主要基于大型消融中心的研究,因为它们包括技术上不均匀的干预措施,以及不同类型 AF 的人群。我们的研究目的是评估和分层阵发性 AF 患者单次 RFCA 后 6 个月和 12 个月 AF 复发的风险,该研究在低容量活动中心进行。我们纳入了 40 名接受初始 RFCA 的患者,随后在 1、3、6 和 12 个月进行连续 48 小时心电图监测。患者通过随机每日桡动脉搏动触诊或心悸时自行监测心脏活动。确定了 10 个晚期 AF 复发的独立预测因素,并使用其中 3 个因素计算了 6 个月风险评分:第一个月的 AF 持续时间、1 至 3 个月之间的 AF 次数以及 6 个月时每 24 小时的室上性早搏次数。该评分可以解释 59%的 AF( = 0.001)。进一步的 12 个月评估确定了三个独立的预测因素。6-12 个月之间存在 AF 是最重要的预测因素(OR = 23.11,95%CI = 3.87-137.83, = 0.001),可以解释 1 年内 45%的 AF。6 个月和 12 个月的风险评分均进行了内部验证。6 个月评分可作为指导低风险患者进一步策略的有用工具,而 12 个月的更长随访可能避免不必要的早期再介入。