Chang Cheng-Yeh, Tseng Tzu-Hsien, Chen Bo-Ru, Wu Yi-Ru, Huang Cheng-Liang, Chen Jui-Chang
Department of Applied Chemistry, National Chiayi University, Chiayi City 600355, Taiwan.
Nanomaterials (Basel). 2021 Oct 25;11(11):2835. doi: 10.3390/nano11112835.
A new strategy using silver nanoparticles (Ag NPs) to synthesize thiolated Au NCs is demonstrated. The quasi-spherical Ag NPs serve as a platform, functioning as a reducing agent for Au (III) and attracting capping ligands to the surface of the Ag NPs. Glutathione disulfide (GSSG) and dithiothreitol (DTT) were used as capping ligands to synthesize thiolated Au NCs (glutathione-Au NCs and DTT-Au NCs). The glutathione-Au NCs and DTT-Au NCs showed red color luminance with similar emission wavelengths (630 nm) at an excitation wavelength of 354 nm. The quantum yields of the glutathione-Au NCs and DTT-Au NCs were measured to be 7.3% and 7.0%, respectively. An electrophoretic mobility assay showed that the glutathione-Au NCs moved toward the anode, while the DTT-Au NCs were not mobile under the electric field, suggesting that the total net charge of the thiolated Au NCs is determined by the charges on the capping ligands. The detection of the K values, 26 M and 0 M, respectively, revealed that glutathione-Au NCs are much more accessible to an aqueous environment than DTT-Au NCs.
展示了一种使用银纳米颗粒（Ag NPs）合成硫醇化金纳米簇（Au NCs）的新策略。准球形的Ag NPs作为一个平台，充当Au（III）的还原剂，并将封端配体吸引到Ag NPs的表面。谷胱甘肽二硫化物（GSSG）和二硫苏糖醇（DTT）被用作封端配体来合成硫醇化金纳米簇（谷胱甘肽-金纳米簇和DTT-金纳米簇）。谷胱甘肽-金纳米簇和DTT-金纳米簇在354nm的激发波长下呈现出红色发光，发射波长相似（630nm）。测得谷胱甘肽-金纳米簇和DTT-金纳米簇的量子产率分别为7.3%和7.0%。电泳迁移率测定表明，谷胱甘肽-金纳米簇向阳极移动，而DTT-金纳米簇在电场下不移动，这表明硫醇化金纳米簇的总净电荷由封端配体上的电荷决定。对K值分别为26 M和0 M的检测表明，谷胱甘肽-金纳米簇比DTT-金纳米簇更容易进入水性环境。
