Division of Critical Care Medicine, Nicklaus Children's Hospital, Miami, Florida; Herbert Wertheim College of Medicine, Florida International University, Miami, Florida.
Florida Poison Information Center, Miami, Florida; Jackson Memorial Hospital, Miami, Florida; University of Miami/Jackson Residency in Emergency Medicine, Miami, Florida.
J Emerg Med. 2022 Feb;62(2):e16-e19. doi: 10.1016/j.jemermed.2021.10.007. Epub 2021 Nov 24.
Diquat is an herbicide that may cause rapid and profound systemic toxicity. It can cause multisystem organ failure, primarily via its effects on the gastrointestinal, renal, cardiovascular, and central nervous systems. Case fatality rates as high as 43% have been reported. There is a paucity of pediatric literature on diquat poisoning, and in this article, we will discuss an unfortunate pediatric case that highlights the severity of diquat toxicity.
We present the case of a child who ingested diquat, which led to multisystem organ failure and death. WHY SHOULD AN EMERGENCY PHYSICIAN BE AWARE OF THIS?: Clinicians should be aware of this herbicide's potential for significant morbidity and mortality, especially in children, in whom small quantities can be lethal. It is important that emergency physicians are aware of the significant toxicity of diquat and provide early gastric decontamination, as it is the only proven therapeutic strategy.
敌草快是一种除草剂,可能导致迅速而严重的全身中毒。它可通过影响胃肠道、肾脏、心血管和中枢神经系统导致多系统器官衰竭。据报道,其病死率高达 43%。有关敌草快中毒的儿科文献很少,在本文中,我们将讨论一个不幸的儿科病例,该病例突出了敌草快毒性的严重性。
我们介绍了一个孩子摄入敌草快导致多系统器官衰竭和死亡的案例。
为什么急诊医生应该了解这种情况?:临床医生应该意识到这种除草剂可能导致严重的发病率和死亡率,特别是在儿童中,少量敌草快即可致命。重要的是,急诊医生应该意识到敌草快的严重毒性,并提供早期的胃去污治疗,因为这是唯一经过证实的治疗策略。