Kumar D, Dawoud B E S, Kent S, Kyzas P
University of Liverpool.
Department of Oral & Maxillofacial Surgery, North Manchester General Hospital, Manchester University NHS Foundation Trust.
Br J Oral Maxillofac Surg. 2022 Apr;60(3):291-294. doi: 10.1016/j.bjoms.2021.05.013. Epub 2021 May 25.
Non-condylar mandibular fractures are consdered 'open' fractures and as such are thought to require prophylactic antibiotics. There is no overall consensus on the optimal regimen or choice of antibiotic in the preoperative and postoperative periods due to a lack of high-quality evidence. We therefore set out to ascertain the current UK-wide practice of antibiotic prescribing for non-condylar mandibular fractures. We used a web-based online survey (Google Forms) that was disseminated via email and social media platforms to oral and maxillofacial surgery (OMFS) consultants and trainees of all grades. The questions focused on usual antibiotic practices and typical clinical management of non-condylar mandibular fractures. We gathered information on preoperative antibiotics, and on perioperative and postoperative periods. We collected data from 50 different UK OMFS units representing a broad snapshot of national practice. The majority of responders were speciality trainees (36%) followed by dental core trainees (34%). A total of 45/50 centres routinely admitted patients, and preoperative intravenous antibiotics were commenced on admission by 77/89 respondents, intravenous being the chosen route in all cases. In the preoperative period 81% prescribe co-amoxiclav. In 91% of cases, open reduction and internal fixation (ORIF) was on general emergency (CEPOD) operating lists, whilst dedicated OMFS trauma lists accounted for 9%. With respect to timing, 49% aimed to carry out ORIF within 24 hours from the time of admission, 44% aimed for surgery within 24 - 48 hours, and 6% aimed for surgery on a semielective basis (48 hours or more). Postoperative antibiotics were prescribed routinely by 88% of responders. Preoperative intravenous prophylactic antibiotics are commonplace in non-condylar mandibular fractures. This UK-wide survey demonstrated significant variability in antibiotic prescribing practices, especially in the postoperative period. Most units still rely on CEPOD emergency theatres to provide the capacity for ORIF in this patient group.
非髁突下颌骨骨折被视为“开放性”骨折,因此被认为需要预防性使用抗生素。由于缺乏高质量证据,对于术前和术后最佳抗生素治疗方案或抗生素选择尚无总体共识。因此,我们着手确定英国目前针对非髁突下颌骨骨折开具抗生素的做法。我们使用了基于网络的在线调查(谷歌表单),通过电子邮件和社交媒体平台分发给各级口腔颌面外科(OMFS)顾问和实习生。问题集中在非髁突下颌骨骨折的常规抗生素使用方法和典型临床管理。我们收集了关于术前抗生素以及围手术期和术后时期的信息。我们从代表全国广泛实践情况的50个不同的英国口腔颌面外科单位收集了数据。大多数受访者是专科实习生(36%),其次是牙科核心实习生(34%)。共有45/50个中心常规收治患者,77/89名受访者在入院时开始使用术前静脉抗生素,所有病例均选择静脉途径。在术前阶段,81%的人开具阿莫西林克拉维酸钾。在91%的病例中,切开复位内固定术(ORIF)在普通急诊(CEPOD)手术清单上,而专门的口腔颌面外科创伤清单占9%。关于时间安排,49%的人旨在入院后24小时内进行切开复位内固定术,44%的人旨在24 - 48小时内进行手术,6%的人旨在半择期进行手术(48小时或更长时间)。88%的受访者常规开具术后抗生素。术前静脉预防性使用抗生素在非髁突下颌骨骨折中很常见。这项全英国范围的调查表明,抗生素开具做法存在显著差异,尤其是在术后阶段。大多数单位仍然依赖CEPOD急诊手术室为该患者群体提供切开复位内固定术的手术能力。