影响轻中度近视儿童脉络膜血管指数的因素。
Factors effecting the choroidal vascularity index in children with mild to moderate myopia.
机构信息
Kırşehir Ahi Evran Training and Research Hospital, Department of Ophthalmology, Kırşehir, Turkey.
Kırşehir Ahi Evran Training and Research Hospital, Department of Ophthalmology, Kırşehir, Turkey.
出版信息
Photodiagnosis Photodyn Ther. 2022 Mar;37:102652. doi: 10.1016/j.pdpdt.2021.102652. Epub 2021 Nov 24.
PURPOSE
To measure the choroidal structural parameters in a population of myopic children and determine the factors effecting the choroidal vascularity index (CVI).
METHODS
In total, 200 eyes of 200 children (100 females, 100 males) with a mean age of 11.5 ± 1.6 years were included in the study. Macular imaging was performed using EDI mode of spectral domain-optical coherence tomography. Binarization of the choroidal area was performed with ImageJ software. Total choroidal area, luminal area (LA), stromal area (SA), and CVI were automatically calculated.
RESULTS
The mean choroidal, stromal and luminal areas were measured as 0.952 ± 0.127 mm, 0.626 ± 0.103 mm and 0.325 ± 0.076 mm, respectively. The mean CVI was 65.81% ± 6.56. Age and the axial length (AL) of the participants were not found to be associated with the LA and the CVI. (r=-0.078, p=0.274, r=0.017, p=0.808, and r=0,051, p=0.474 and r=-0.128, p=0.071, respectively). There was a statistically significant strong association between the LA and CVI measurements and SE of the participants (r=0.736, p=0.001, and r=-0.605; p=0.001).
CONCLUSION
Age and AL were not associated with the CVI, but SE was significantly associated with the CVI.
目的
测量近视儿童人群的脉络膜结构参数，并确定影响脉络膜血管指数（CVI）的因素。
方法
本研究共纳入 200 名年龄在 11.5±1.6 岁的近视儿童（100 名女性，100 名男性）的 200 只眼。使用频域光学相干断层扫描的 EDI 模式进行黄斑成像。使用 ImageJ 软件对脉络膜区域进行二值化处理。自动计算总脉络膜面积、管腔面积（LA）、基质面积（SA）和 CVI。
结果
测量的脉络膜、基质和管腔面积分别为 0.952±0.127mm、0.626±0.103mm 和 0.325±0.076mm。平均 CVI 为 65.81%±6.56%。参与者的年龄和眼轴（AL）与 LA 和 CVI 无关。（r=-0.078，p=0.274，r=-0.017，p=0.808，r=0.051，p=0.474 和 r=-0.128，p=0.071）。LA 和 CVI 测量值与参与者的等效球镜（SE）之间存在统计学上显著的强相关性（r=0.736，p=0.001，和 r=-0.605；p=0.001）。
结论
年龄和 AL 与 CVI 无关，但 SE 与 CVI 显著相关。
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