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支架辅助弹簧圈栓塞术后显著缩小的部分血栓形成的巨大基底尖动脉瘤,同时伴新生血管消失。

Partially thrombosed giant basilar tip aneurysm that remarkably decreased in size after stent-assisted coiling associated with the disappearance of neovascularization.

机构信息

Department of Neurosurgery, Showa University Fujigaoka Hospital, 1-30 Fujigaoka, Aobaku, Yokohama City, Kanagawa, 227-8501, Japan.

Department of Neurosurgery, Showa University Northern Yokohama Hospital, Yokohama City, Kanagawa, Japan.

出版信息

Neuroradiology. 2022 Apr;64(4):837-841. doi: 10.1007/s00234-021-02867-9. Epub 2021 Nov 27.

DOI:10.1007/s00234-021-02867-9
PMID:34839378
Abstract

Endovascular treatment for partially thrombosed giant basilar tip aneurysms has not been established because of its low cure rate and numerous associated comorbidities. Although some authors reported the growth mechanism of partially thrombosed aneurysm, there is no report for the process of its shrinkage after treatment. We describe a case of a partially thrombosed giant basilar tip aneurysm presenting with disturbance of consciousness because of a mass effect and brain edema. The patient underwent stent-assisted coiling using a low-profile visualized intraluminal support stent (Terumo). Although pre-operative magnetic resonance imaging (MRI) and angiography revealed prominent neovascularization of the inner aneurysmal layer, this vessel was absent on follow-up angiography 1 month after treatment. Repeat angiography demonstrated the gradual recanalization of the aneurysm. However, repeat MRI examinations showed remarkable shrinkage of the thrombosed aneurysm, and the complete disappearance of the thrombosed component was noted 6 months after treatment. The disappearance of neovascularization 1 month after the treatment may have contributed to the shrinkage of the thrombosed aneurysm. Stent-assisted coiling combined with alteration caused a hemodynamic change in this aneurysm, and the flow-diverting effect might have controlled this partially thrombosed giant aneurysm.

摘要

部分血栓形成的巨大基底尖动脉瘤的血管内治疗尚未确立,因为其治愈率低,且存在许多相关的合并症。尽管一些作者报道了部分血栓形成动脉瘤的生长机制,但尚无关于其治疗后缩小过程的报道。我们描述了一例部分血栓形成的巨大基底尖动脉瘤病例,该患者因占位效应和脑水肿而出现意识障碍。患者接受了使用低轮廓可视化腔内支撑支架(Terumo)的支架辅助线圈栓塞治疗。尽管术前磁共振成像(MRI)和血管造影显示内层动脉瘤内有明显的新生血管化,但治疗后 1 个月的随访血管造影显示该血管缺失。再次血管造影显示动脉瘤逐渐再通。然而,重复 MRI 检查显示血栓形成的动脉瘤显著缩小,治疗后 6 个月时注意到血栓形成部分完全消失。治疗后 1 个月新生血管的消失可能导致血栓形成的动脉瘤缩小。支架辅助线圈栓塞联合改变引起了该动脉瘤的血流动力学变化,可能通过血流导向效应控制了这个部分血栓形成的巨大动脉瘤。

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Partially thrombosed giant basilar tip aneurysm that remarkably decreased in size after stent-assisted coiling associated with the disappearance of neovascularization.支架辅助弹簧圈栓塞术后显著缩小的部分血栓形成的巨大基底尖动脉瘤,同时伴新生血管消失。
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