Department of Otolaryngology-Head and Neck Surgery, Soroka Medical School, Ben Gurion University of the Negev, Beer-Sheva, Israel.
Department of Otolaryngology-Head and Neck Surgery, Toronto General Hospital, University Health Network, University of Toronto, 200 Elizabeth Street, 8N-873, Toronto, ON, M5G 2C4, Canada.
Eur Arch Otorhinolaryngol. 2022 Aug;279(8):3911-3916. doi: 10.1007/s00405-021-07155-z. Epub 2021 Nov 28.
It is generally accepted that headshake nystagmus (HSN) is generated from an asymmetrical peripheral vestibular input and a correlation exists between HSN and canal paresis. There have been limited reports, however, how HSN correlates with the more recently introduced tests of vestibular function.
AIMS/OBJECTIVES: To evaluate the correlation between HSN and unilateral weakness on caloric testing, high-frequency vestibulo-ocular reflex (VOR) function on video head impulse testing (VHIT) and otolith function determined by vestibular evoked myogenic potentials (VEMPs).
A retrospective study of all patients who underwent complete vestibular function testing at our tertiary referral center from 2016 to 2019 was performed. Demographic data, clinical diagnosis (where available), the results of video-nystagmography, vHIT, and VEMPs were evaluated.
Of the 1499 patients in the study period, 101 (6.7%) had HSN. Vestibular test abnormalities were more common in patients with HSN. The sensitivity of HSN for underlying pathology was low in comparison with vestibular testing. However, HSN demonstrated a high specificity.
HSN generation is likely more complex than caloric-induced nystagmus, probably due to additional variables within the vestibular system. HSN may provide clinicians with additional information concerning high-frequency VOR function involving lateral semicircular and otolith dysfunction.
人们普遍认为摇头性眼震（HSN）是由不对称的外周前庭输入产生的，HSN 与管腔麻痹之间存在相关性。然而，关于 HSN 与最近引入的前庭功能测试之间的相关性的报道有限。
目的/目标：评估 HSN 与冷热试验单侧无力、视频头脉冲试验（VHIT）高频前庭眼反射（VOR）功能和前庭诱发肌源性电位（VEMPs）确定的耳石功能之间的相关性。
对 2016 年至 2019 年在我们的三级转诊中心进行完整前庭功能测试的所有患者进行了回顾性研究。评估了人口统计学数据、临床诊断（如有）、视频眼震图、VHIT 和 VEMPs 的结果。
在研究期间的 1499 名患者中，有 101 名（6.7%）出现 HSN。HSN 患者的前庭测试异常更为常见。与前庭测试相比，HSN 对潜在病理的敏感性较低，但特异性较高。
HSN 的产生可能比冷热诱发的眼震更为复杂，这可能是由于前庭系统内的其他变量。HSN 可能为临床医生提供有关涉及外侧半规管和耳石功能的高频 VOR 功能的额外信息。
