Department of Microbial Ecology, Ocean University of China, Qingdao 266003, PR China.
Department of Microbial Ecology, Ocean University of China, Qingdao 266003, PR China.
Mar Pollut Bull. 2022 Feb;175:113165. doi: 10.1016/j.marpolbul.2021.113165. Epub 2021 Nov 25.
The ecotoxicity of nitrofurazone was analyzed based on a community-based approach using periphytic protozoa. Median lethal concentrations (LC) within an exposure time of 30 min were determined by an acute toxicity test at 0, 1.5, 3, 6 and 12 mg ml nitrofurazone. Toxicity curve tests demonstrated a decreasing trend with increasing exposure time and was well fitted to the toxicity equation LC = 32.85e (t = exposure time; R = 0.91; P < 0.05). Median inhibition concentrations (IC) for periphytic protozoan growth rates were obtained by chronic tests at 0, 1, 2, 4 and 8 mg ml nitrofurazone within 10 days exposure and were well fitted to the equation r = 0.3686e (C is the concentration of nitrofurazone; R = 0.92 and P < 0.05). These findings suggest that the LC and IC values of nitrofurazone can be predicted for any exposure time using periphytic protozoan communities as a bioassay model.
基于采用附生原生动物的群落方法，分析了呋喃西林的生态毒性。在 0、1.5、3、6 和 12mg/ml 呋喃西林暴露 30 分钟的急性毒性试验中，确定了中位致死浓度 (LC)。毒性曲线试验表明，随着暴露时间的增加，毒性呈下降趋势，与毒性方程 LC=32.85e（t=暴露时间；R=0.91；P<0.05）拟合良好。在 0、1、2、4 和 8mg/ml 呋喃西林暴露 10 天的慢性试验中，获得了对附生原生动物生长率的中位抑制浓度 (IC)，并与方程 r=0.3686e（C 为呋喃西林的浓度；R=0.92 和 P<0.05）拟合良好。这些发现表明，使用附生原生动物群落作为生物测定模型，可以预测呋喃西林在任何暴露时间的 LC 和 IC 值。
