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鞘内吗啡镇痛泵继发严重尿潴留:一例报告

Severe urinary retention secondary to intrathecal morphine pain pump: A case report.

作者信息

Fregene Eyitemi, Lotze Peter

机构信息

The Woman's Hospital of Texas, 7600 Fannin St, Houston, TX, 77054, USA.

HCA Houston Healthcare West OB/GYN Residency Program/ University of Houston, 12141 Richmond Ave, Houston, TX, 77082, USA.

出版信息

Urol Case Rep. 2021 Nov 9;40:101935. doi: 10.1016/j.eucr.2021.101935. eCollection 2022 Jan.

DOI:10.1016/j.eucr.2021.101935
PMID:34840958
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8607156/
Abstract

Intrathecal opioid pain pumps (IPP) are sometimes prescribed for treatment of chronic nonmalignant pain. Severe urinary retention is not a commonly reported side effect of the IPP. In this case, an elderly female with multiple comorbidities presented with acute onset of severe urinary retention immediately following morphine IPP placement for chronic peripheral neuropathy. Multiple management strategies for urinary retention were employed. However, the urinary retention only fully resolved once the IPP was disabled. This case highlights the need to closely monitor chronic pain patients with complex medical histories who may be uniquely predisposed to opioid-mediated severe urinary retention.

摘要

鞘内阿片类药物止痛泵(IPP)有时会被用于治疗慢性非恶性疼痛。严重尿潴留并非IPP常见的副作用报道。在此病例中,一名患有多种合并症的老年女性在因慢性周围神经病变放置吗啡IPP后,立即出现了急性严重尿潴留。针对尿潴留采用了多种处理策略。然而,只有在停用IPP后,尿潴留才完全缓解。该病例凸显了对于有复杂病史、可能特别易患阿片类药物介导的严重尿潴留的慢性疼痛患者进行密切监测的必要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f011/8607156/ce80ab611a5b/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f011/8607156/f39633b9df4e/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f011/8607156/ce80ab611a5b/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f011/8607156/f39633b9df4e/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f011/8607156/ce80ab611a5b/gr2.jpg

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本文引用的文献

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Systematic review of interventions for the prevention and treatment of postoperative urinary retention.系统评价预防和治疗术后尿潴留的干预措施。
BJS Open. 2018 Nov 19;3(1):11-23. doi: 10.1002/bjs5.50114. eCollection 2019 Feb.
2
Spinal morphine in nonmalignant chronic pain: a retrospective study in 39 patients.脊髓吗啡治疗非恶性慢性疼痛:39 例回顾性研究。
Neuromodulation. 2002 Jul;5(3):150-9. doi: 10.1046/j.1525-1403.2002.02025.x.
3
Postoperative urinary retention: anesthetic and perioperative considerations.术后尿潴留:麻醉及围手术期相关考量
Anesthesiology. 2009 May;110(5):1139-57. doi: 10.1097/ALN.0b013e31819f7aea.
4
Programmable intrathecal opioid delivery systems for chronic noncancer pain: a systematic review of effectiveness and complications.用于慢性非癌性疼痛的可编程鞘内阿片类药物输送系统:有效性和并发症的系统评价
Clin J Pain. 2007 Feb;23(2):180-95. doi: 10.1097/01.ajp.0000210955.93878.44.
5
Reversible urinary retention secondary to excessive morphine delivered by an intrathecal morphine pump.鞘内吗啡泵输注过量吗啡导致的可逆性尿潴留。
Spine (Phila Pa 1976). 1994 Mar 15;19(6):719-20. doi: 10.1097/00007632-199403001-00013.