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艾滋病患者胃肠道的多灶性异常

Multifocal abnormalities of the gastrointestinal tract in AIDS.

作者信息

Wall S D, Ominsky S, Altman D F, Perkins C L, Sollitto R, Goldberg H I, Margulis A R

出版信息

AJR Am J Roentgenol. 1986 Jan;146(1):1-5. doi: 10.2214/ajr.146.1.1.

DOI:10.2214/ajr.146.1.1
PMID:3484397
Abstract

On review of 63 barium sulfate examinations in 44 patients with acquired immunodeficiency syndrome (AIDS), 61% of the 23 single-contrast examinations and 98% of the 40 double-contrast examinations were abnormal. Abnormalities involved all areas of the gastrointestinal (GI) tract and covered a wide spectrum of findings including thickened folds, nodularity, increased secretions, superficial erosions, ulcerations, plaque formation, and tumor mass. Abnormalities, when present, were most commonly multifocal (three or more sites) on upper GI study (64%) and barium enema (69%). Thirty-eight patients (86%) had at least one abnormal study; 27 of these patients had multifocal disease in either the upper or lower tract separately or combined. The most common site of abnormality was the duodenum on upper GI study and the sigmoid colon on barium enema. In 27 cases the radiographic abnormalities could be specifically correlated with a malignancy or an opportunistic infection by endoscopy, colonoscopy, culture, biopsy, or autopsy. Multifocal disease of the upper and/or lower GI tract, especially when the duodenum is involved, should suggest AIDS even in patients not thought to be at high risk for the disease.

摘要

在对44例获得性免疫缺陷综合征(AIDS)患者的63次硫酸钡检查进行回顾时,23次单对比检查中有61%异常,40次双对比检查中有98%异常。异常累及胃肠道(GI)的所有区域,涵盖广泛的表现,包括黏膜皱襞增厚、结节状、分泌物增多、浅表糜烂、溃疡、斑块形成和肿瘤肿块。在上消化道造影(64%)和钡灌肠检查(69%)中,异常情况出现时最常见为多灶性(三个或更多部位)。38例患者(86%)至少有一项检查异常;其中27例患者在上消化道或下消化道单独或合并出现多灶性病变。异常最常见的部位在上消化道造影中是十二指肠,在钡灌肠检查中是乙状结肠。在27例病例中,影像学异常可通过内镜检查、结肠镜检查、培养、活检或尸检与恶性肿瘤或机会性感染明确相关。上消化道和/或下消化道的多灶性病变,尤其是累及十二指肠时,即使在被认为患该病风险不高的患者中也应怀疑AIDS。

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Multifocal abnormalities of the gastrointestinal tract in AIDS.艾滋病患者胃肠道的多灶性异常
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