新冠病毒信使核糖核酸疫苗在使用肿瘤坏死因子抑制剂治疗的青少年特发性关节炎青少年中的免疫原性。 - Suppr

Immunogenicity of the COVID-19 mRNA vaccine in adolescents with juvenile idiopathic arthritis on treatment with TNF inhibitors.

作者信息

Dimopoulou Dimitra, Vartzelis George, Dasoula Foteini, Tsolia Maria, Maritsi Despoina

机构信息

Infectious Diseases' Unit, Second Department of Paediatrics, 'P. & A. Kyriakou' Children's Hospital, National and Kapodistrian University, Athens, Greece

Second Department of Pediatrics, 'P. & A. Kyriakou' Children's Hospital, National and Kapodistrian University, Athens, Greece.

出版信息

Ann Rheum Dis. 2022 Apr;81(4):592-593. doi: 10.1136/annrheumdis-2021-221607. Epub 2021 Nov 29.

DOI:10.1136/annrheumdis-2021-221607

PMID:34844930

Abstract

摘要

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Immunogenicity of the COVID-19 mRNA vaccine in adolescents with juvenile idiopathic arthritis on treatment with TNF inhibitors.新冠病毒信使核糖核酸疫苗在使用肿瘤坏死因子抑制剂治疗的青少年特发性关节炎青少年中的免疫原性。

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Methotrexate and glucocorticoids, but not anticytokine therapy, impair the immunogenicity of a single dose of the BNT162b2 mRNA COVID-19 vaccine in patients with chronic inflammatory arthritis.甲氨蝶呤和糖皮质激素会削弱单剂量BNT162b2 mRNA新冠疫苗在慢性炎症性关节炎患者中的免疫原性，但抗细胞因子疗法不会。

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Immunogenicity 6 months post COVID-19 mRNA vaccination among adolescents with juvenile idiopathic arthritis on treatment with TNF inhibitors.COVID-19 mRNA 疫苗接种 6 个月后，接受 TNF 抑制剂治疗的青少年特发性关节炎患者的免疫原性。

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Safety and tolerability of the COVID-19 messenger RNA vaccine in adolescents with juvenile idiopathic arthritis treated with tumor necrosis factor inhibitors.新冠信使核糖核酸疫苗在接受肿瘤坏死因子抑制剂治疗的青少年特发性关节炎青少年中的安全性和耐受性。

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Safety and immunogenicity of a modified mRNA-lipid nanoparticle vaccine candidate against COVID-19: Results from a phase 1, dose-escalation study.针对 COVID-19 的一种改良信使核糖核酸-脂质纳米颗粒候选疫苗的安全性和免疫原性：一项 1 期、剂量递增研究的结果。

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Immunogenicity of the COVID-19 mRNA vaccine in adolescents with juvenile idiopathic arthritis on treatment with TNF inhibitors.

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