Orthopedics. 2022 Jan-Feb;45(1):57-63. doi: 10.3928/01477447-20211124-01. Epub 2021 Dec 2.
Revision total hip arthroplasty (rTHA) after septic failure is associated with higher morbidity and mortality compared with aseptic revisions. The goals of this study were to characterize (1) the in-hospital mortality rate for patients with septic rTHA, (2) the effect of hospital hip revision surgery volume (HRV) on mortality after septic rTHA, and (3) the independent risk factors associated with in-hospital mortality rates after rTHA with 2-year follow-up. The authors analyzed the Healthcare Cost and Utilization Project State Inpatient Databases of New York and Florida to identify cases of septic rTHA from 2007 to 2012 with codes. The authors included patients with (1) no history of THA for 2 years before the index admission and (2) 2 years of follow-up. Groups with primary THA and aseptic rTHA were identified as control groups. Logistic regression was used to evaluate independent associations. Of 3057 patients with septic rTHA, 5.2% (n=160) had in-hospital mortality vs 2.9% of those with primary THA (n=3525, =.0001) and 2.1% of those with aseptic rTHA (n=252, =.0001). Octogenarian status, medium-risk Elixhauser comorbidity score, and high-risk Elixhauser comorbidity score were independent risk factors for mortality (adjusted odds ratio [AOR]=1.587, 95% CI=1.103-2.282, =.0128; AOR=2.439, 95% CI=1.680-3.541, <.0001; and AOR=6.367, 95% CI=4.134-9.804, <.0001, respectively). Undergoing rTHA in a high-HRV hospital was associated with lower odds of in-hospital mortality (AOR=0.539, 95% CI=0.332-0.877, =.0127). Receiving care in a low-HRV hospital increased the risk of 2-year postoperative patient mortality. Similarly, older age and a higher comorbidity burden were independently associated with increased 2-year postoperative mortality. [. 2022;45(1):57-63.].
翻修后感染的全髋关节置换术(rTHA)的发病率和死亡率均高于无菌翻修术。本研究的目的是:(1)描述翻修后感染的 rTHA 患者的院内死亡率;(2)分析医院髋关节翻修手术量(HRV)对翻修后感染 rTHA 死亡率的影响;(3)分析与 rTHA 后 2 年随访期间院内死亡率相关的独立危险因素。作者分析了纽约州和佛罗里达州医疗保健成本和利用项目州住院数据库 2007 年至 2012 年的病例数据,使用了 ICD-9-CM 编码识别翻修后感染的 rTHA 病例。纳入标准为:(1)在指数入院前 2 年内无 THA 病史;(2)有 2 年的随访数据。将初次 THA 和无菌 rTHA 患者组作为对照组。采用 logistic 回归评估独立相关性。在 3057 例翻修后感染 rTHA 患者中,5.2%(n=160)患者院内死亡,而初次 THA 患者的死亡率为 2.9%(n=3525,P<.0001),无菌 rTHA 患者的死亡率为 2.1%(n=252,P<.0001)。80 岁以上、中危 Elixhauser 合并症评分和高危 Elixhauser 合并症评分是死亡的独立危险因素(调整后的优势比[OR]为 1.587,95%置信区间[CI]为 1.103-2.282,P=.0128;OR=2.439,95%CI 为 1.680-3.541,P<.0001;OR=6.367,95%CI 为 4.134-9.804,P<.0001)。在高 HRV 医院进行 rTHA 与较低的院内死亡率相关(OR=0.539,95%CI 为 0.332-0.877,P=.0127)。在低 HRV 医院接受治疗增加了 2 年术后患者死亡的风险。同样,年龄较大和合并症负担较高与 2 年术后死亡率的增加独立相关。