Division of Organic Chemistry, CSIR-National Chemical Laboratory, Pune 411008, India.
Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002, India.
Chem Commun (Camb). 2021 Dec 14;57(99):13582-13585. doi: 10.1039/d1cc05997a.
An iron(III) catalyzed tandem ring opening/1,6-conjugate addition of cyclopropanols to -quinone methides leading to γ,γ-diaryl ketones has been described. This catalytic protocol provides a novel and efficient method to access γ,γ-diaryl ketone derivatives in good to excellent yields with high functional group tolerance. Importantly, γ,γ-diaryl ketone can be further functionalized to give a versatile set of useful products.
一种铁(III)催化的环丙醇与 - 醌甲硅烷的串联开环/1,6-共轭加成反应，生成γ,γ-二芳基酮，已经被描述。这种催化方案提供了一种新颖而有效的方法，以良好至优秀的产率获得高官能团耐受性的γ,γ-二芳基酮衍生物。重要的是，γ,γ-二芳基酮可以进一步官能化，得到一组用途广泛的有用产物。
