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[非麻醉去脑蛙的超长潜伏期躯体交感反应]

[Super-long latent somato-sympathetic response in non-anesthesized decerebrate frogs].

作者信息

Frolenkov G I, Lukoshkova E V, Khaiutin V M

出版信息

Biull Eksp Biol Med. 1986 Jan;101(1):3-5.

PMID:3484640
Abstract

Somato-sympathetic reflex responses were studied by recording the activity of the renal sympathetic efferents following excitation of sciatic nerve A-afferents in immobilized decerebrated frogs before and during viadril-induced anesthesia. Apart from A-response reported in anesthetized frogs and consisting of excitatory and inhibitory components, in non-anesthetized frogs reflex discharge with a latency over 2 sec was revealed. Unlike the former one, this response disappeared after intravenous injection of viadril. In the same frogs intravenous injection of viadril converted pressor reflexes in response to stimulation of sciatic nerve A-afferents into depressor ones. A-response with superlong latency is assumed to reflect the excitation of those central structures that are responsible for the development of pressor reflexes to somatic A-fiber stimulation. In this respect the described somato-sympathetic A-response seems to be analogous to the very late A-response in the mammals.

摘要

在维阿德里尔诱导麻醉前后,通过记录固定去脑青蛙坐骨神经A类传入纤维兴奋后肾交感传出纤维的活动,研究了躯体 - 交感反射反应。除了在麻醉青蛙中报道的由兴奋和抑制成分组成的A反应外,在未麻醉的青蛙中还发现了潜伏期超过2秒的反射放电。与前者不同,这种反应在静脉注射维阿德里尔后消失。在同一只青蛙中,静脉注射维阿德里尔使对坐骨神经A类传入纤维刺激的升压反射转变为降压反射。超长潜伏期的A反应被认为反映了那些负责对躯体A纤维刺激产生升压反射的中枢结构的兴奋。在这方面,所描述的躯体 - 交感A反应似乎类似于哺乳动物中非常晚出现的A反应。

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