Bennett C L, Putterman A, Bitran J D, Recant W, Shapiro C M, Karesh J, Kalokhe U
Cancer. 1986 Mar 15;57(6):1204-8. doi: 10.1002/1097-0142(19860315)57:6<1204::aid-cncr2820570624>3.0.co;2-2.
Ten patients with non-Hodgkin's lymphoma primarily affecting the orbital region were evaluated at Michael Reese Hospital and Medical Center, Chicago, between 1976 and 1983. Diagnoses were based on the histopathologic classification systems of the Working Formulation of the Non-Hodgkin's Lymphomas and Rappoport. Sequential staging procedures performed at the time of diagnosis included liver-spleen scans, Technecium-99 bone scans, gallium 67 scans, computerized axial tomograms of the orbit and abdomen, bone marrow examination and cerebral spinal fluid analyses. Adverse prognostic factors included the following: orbital bone erosions, Stage IV disease, and large cell or mixed cell, diffuse histologic features. The type of histopathologic findings combined with the results of sequential staging procedures is useful in identifying those patients who would benefit most from systemic chemotherapy.
1976年至1983年间，在芝加哥迈克尔·里斯医院及医疗中心对10例主要累及眼眶区域的非霍奇金淋巴瘤患者进行了评估。诊断依据非霍奇金淋巴瘤工作方案和拉波波特的组织病理学分类系统。诊断时进行的连续分期程序包括肝脾扫描、锝-99骨扫描、镓67扫描、眼眶和腹部的计算机断层扫描、骨髓检查和脑脊液分析。不良预后因素包括：眼眶骨质侵蚀、IV期疾病以及大细胞或混合细胞弥漫性组织学特征。组织病理学检查结果类型与连续分期程序的结果相结合，有助于识别那些将从全身化疗中获益最大的患者。
