Herstein Jocelyn J, Wolf Timo, Nicastri Emanuele, Leo Yee Sin, Lim Poh Lian, Jacobs Michael, Vanairsdale Sharon, Toner Eric, Shearer Matthew P, Vasa Angela, Mukherjee Vikram, Echeverri Andrea, Shenoy Erica S, Lowe John J
University of Nebraska Medical Center, Omaha, Nebraska, United States.
University Hospital Frankfurt, Frankfurt am Main, Germany.
Infect Control Hosp Epidemiol. 2022 Nov;43(11):1679-1685. doi: 10.1017/ice.2021.477. Epub 2021 Dec 1.
To assess experience, physical infrastructure, and capabilities of high-level isolation units (HLIUs) planning to participate in a 2018 global HLIU workshop hosted by the US National Emerging Special Pathogens Training and Education Center (NETEC).
An electronic survey elicited information on general HLIU organization, operating costs, staffing models, and infection control protocols of select global units.
The survey was distributed to site representatives of 22 HLIUs located in the United States, Europe, and Asia; 19 (86%) responded.
Data were coded and analyzed using descriptive statistics.
The mean annual reported budget for the 19 responding units was US$484,615. Most (89%) had treated a suspected or confirmed case of a high-consequence infectious disease. Reported composition of trained teams included a broad range of clinical and nonclinical roles. The mean number of HLIU beds was 6.37 (median, 4; range, 2-20) for adults and 4.23 (median, 2; range, 1-10) for children; however, capacity was dependent on pathogen.
Responding HLIUs represent some of the most experienced HLIUs in the world. Variation in reported unit infrastructure, capabilities, and procedures demonstrate the variety of HLIU approaches. A number of technical questions unique to HLIUs remain unanswered related to physical design, infection prevention and control procedures, and staffing and training. These key areas represent potential focal points for future evidence and practice guidelines. These data are important considerations for hospitals considering the design and development of HLIUs, and there is a need for continued global HLIU collaboration to define best practices.
评估计划参加由美国国家新兴特殊病原体培训与教育中心(NETEC)主办的2018年全球高级隔离单元(HLIU)研讨会的高级隔离单元的经验、物理基础设施和能力。
一项电子调查收集了有关选定全球单元的HLIU总体组织、运营成本、人员配备模式和感染控制协议的信息。
该调查分发给位于美国、欧洲和亚洲的22个HLIU的现场代表;19个(86%)做出了回应。
使用描述性统计对数据进行编码和分析。
19个做出回应的单元报告的年平均预算为484,615美元。大多数(89%)曾治疗过高后果传染病的疑似或确诊病例。报告的受过培训的团队组成包括广泛的临床和非临床角色。成人HLIU床位的平均数为6.37(中位数为4;范围为2 - 20),儿童为4.23(中位数为2;范围为1 - 10);然而,容量取决于病原体。
做出回应的HLIU代表了世界上一些经验最丰富的HLIU。报告的单元基础设施、能力和程序的差异表明了HLIU方法的多样性。与物理设计、感染预防和控制程序以及人员配备和培训相关的一些HLIU特有的技术问题仍未得到解答。这些关键领域是未来证据和实践指南的潜在重点。这些数据是考虑设计和开发HLIU的医院的重要考虑因素,并且需要持续的全球HLIU合作来确定最佳实践。