Department of Medical Oncology, Leeds Teaching Hospitals NHS Foundation Trust, Leeds, UK
Department of Haematology, Manchester University NHS Foundation Trust, Manchester, UK.
BMJ Case Rep. 2021 Nov 30;14(11):e243310. doi: 10.1136/bcr-2021-243310.
Plasmablastic lymphoma (PBL) is an uncommon and aggressive type of mature B cell lymphoma rarely involving gastrointestinal (GI) tract. Here, we describe a case of PBL involving the colon in HIV/Epstein-Barr virus negative immunocompetent patient who presented with anaemia and weight loss but no significant GI symptoms. It emphasises that even in the absence of classical risk factors, one should consider possibility of this condition as this is potentially curable. Also, we would like to highlight the diagnostic and treatment challenges of such an aggressive lymphoma in a frail elderly patient with multiple comorbidities.
浆母细胞淋巴瘤（PBL）是一种罕见且侵袭性的成熟 B 细胞淋巴瘤，很少累及胃肠道（GI）。在此，我们描述了一例 HIV/Epstein-Barr 病毒阴性免疫功能正常的患者发生结肠 PBL 的病例，该患者表现为贫血和体重减轻，但无明显的 GI 症状。这强调了即使没有典型的危险因素，也应考虑到这种情况的可能性，因为这种情况是可以治愈的。此外，我们还想强调在一位身体虚弱且合并多种疾病的老年患者中，这种侵袭性淋巴瘤的诊断和治疗所面临的挑战。
