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交联术后角膜炎中角膜水肿的快速自发消退。

Rapid spontaneous resolution of corneal hydrops in post-CXL keratitis.

机构信息

Dr Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, Delhi, India

Dr Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, Delhi, India.

出版信息

BMJ Case Rep. 2021 Nov 30;14(11):e246141. doi: 10.1136/bcr-2021-246141.

Abstract

An 11-year-old boy presented with right eye post-Corneal Collagen Cross-Linking (CXL) keratitis, which was complicated by acute corneal hydrops (CH). Keratitis was managed by topical antibiotics, and CH was managed conservatively. Cornea was monitored with serial anterior segment optical coherence tomography (ASOCT) scans. Spontaneous resolution of CH usually takes 8-12 weeks, but in this case it completely resolved in 3 weeks. Rapid resolution of CH after post-CXL keratitis could be attributed to a thinner cornea, increased interlamellar cohesive strength between collagen fibrils of corneal stroma coupled with normal functioning endothelial pump.

摘要

一名 11 岁男孩右眼行角膜胶原交联(CXL)术后出现角膜炎,并合并急性角膜水肿(CH)。角膜炎经局部应用抗生素治疗,CH 则行保守治疗。通过连续的眼前节光学相干断层扫描(ASOCT)监测角膜。CH 通常在 8-12 周内自发缓解,但本例在 3 周内完全缓解。CXL 术后角膜炎的 CH 迅速缓解可能归因于角膜变薄、角膜基质胶原纤维层间黏附力增加,以及内皮泵正常功能。

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