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与平衡缺陷和癫痫发作相关的犬脑干听觉反应异常。

Abnormalities of the brainstem auditory response of the dog associated with equilibrium deficit and seizure.

作者信息

Myers L J, Redding R W, Wilson S

出版信息

Vet Res Commun. 1986 Jan;10(1):73-8. doi: 10.1007/BF02213967.

Abstract

The brainstem auditory evoked response (BAER) was recorded from 20 dogs, 10 exhibited vestibular deficit, and 10 presented with a history of seizures. Two dogs exhibited both types of signs. Abnormalities of the BAER, prolonged interwave latency, were seen in 8 of the 10 animals with vestibular problems, and in 7 of the 10 animals with seizure history. Several different diagnosis were associated with BAER abnormalities in both groups of animals. In 55.5% of the cases exhibiting abnormalities of the BAER, postmortem evidence of brainstem pathology was not detected. The electroencephalogram (EEG) was normal in three instances of abnormalities of the BAER. The BAER was normal in three dogs with abnormalities of the EEG. The BAER is presented as a useful diagnostic tool for brain lesions in animals with vestibular deficit and seizure history, but appears most useful when used in conjunction with the EEG. Correlations of abnormalities of the BAER and clinical course of disease are discussed.

摘要

对20只犬记录了脑干听觉诱发电位(BAER),其中10只存在前庭功能障碍,10只曾有癫痫发作史。有2只犬表现出两种症状。在10只患有前庭问题的动物中,有8只BAER出现异常,即波间潜伏期延长;在10只曾有癫痫发作史的动物中,有7只出现同样情况。两组动物中,几种不同的诊断结果都与BAER异常有关。在出现BAER异常的病例中,55.5%未检测到脑干病理改变的尸检证据。在3例BAER异常的病例中,脑电图(EEG)正常。在3例EEG异常的犬中,BAER正常。BAER被认为是一种用于诊断有前庭功能障碍和癫痫发作史动物脑损伤的有用工具,但与EEG联合使用时似乎最有用。文中讨论了BAER异常与疾病临床病程的相关性。

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