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胎儿心脏介入与胎儿心脏手术:21世纪我们处于什么阶段?

Fetal cardiac intervention and fetal cardiac surgery: where are we in 21st century?

作者信息

Halder Vikram, Ghosh Soumitra, Shrimanth Yamasandi Siddegowda, Manoj Rohit Kumar, Mandal Banashree, Thingnam Shyam Kumar Singh, Kumar Rupesh

机构信息

Department of Cardiothoracic and Vascular Surgery, Advanced Cardiac Center, Postgraduate Institute of Medical Education and Research Chandigarh 160012, India.

Department of Cardiology, Advanced Cardiac Center, Postgraduate Institute of Medical Education and Research Chandigarh 160012, India.

出版信息

Am J Cardiovasc Dis. 2021 Oct 25;11(5):642-646. eCollection 2021.

PMID:34849297
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8611270/
Abstract

Fetal cardiac intervention is an in-utero cardiac procedure done in fetuses with heart diseases like severe aortic stenosis with evolving hypoplastic left heart syndrome, hypoplastic left heart syndrome with an intact or restricted atrial septum, pulmonary atresia with an intact ventricular septum, fetal heart block obstructed total anomalous pulmonary venous return, pericardial collection. The successful biventricular repair can be done in postnatal life after aortic or pulmonary valvuloplasty. Fetal bypass is very challenging because of different physiology. Low prime volume with the high flow can be used to prevent an inflammatory response.

摘要

胎儿心脏介入是一种针对患有心脏病的胎儿在子宫内进行的心脏手术,这些心脏病包括严重主动脉瓣狭窄合并逐渐发展的左心发育不全综合征、房间隔完整或受限的左心发育不全综合征、室间隔完整的肺动脉闭锁、胎儿心脏传导阻滞、完全性肺静脉异位引流梗阻、心包积液。在进行主动脉或肺动脉瓣成形术后,可在出生后进行成功的双心室修复。由于生理情况不同,胎儿体外循环极具挑战性。可采用低预充量和高流量来预防炎症反应。

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Fetal aortic valvuloplasty: first report of two cases from Saudi Arabia.胎儿主动脉瓣成形术:沙特阿拉伯两例病例的首次报告。
J Cardiothorac Surg. 2020 Jun 22;15(1):150. doi: 10.1186/s13019-020-01195-y.
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Fetal interventions for structural heart disease.胎儿结构性心脏病的干预措施。
Echocardiography. 2017 Dec;34(12):1834-1841. doi: 10.1111/echo.13667.
3
International Fetal Cardiac Intervention Registry: A Worldwide Collaborative Description and Preliminary Outcomes.国际胎儿心脏介入登记处:全球协作描述和初步结果。
J Am Coll Cardiol. 2015 Jul 28;66(4):388-99. doi: 10.1016/j.jacc.2015.05.037.
4
Left Ventricular Remodeling and Function in Children with Biventricular Circulation After Fetal Aortic Valvuloplasty.胎儿主动脉瓣成形术后双心室循环儿童的左心室重构与功能
Pediatr Cardiol. 2015 Oct;36(7):1502-9. doi: 10.1007/s00246-015-1193-6. Epub 2015 May 15.
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Fetal cardiac interventions.
Pediatr Neonatol. 2015 Apr;56(2):81-7. doi: 10.1016/j.pedneo.2014.04.007. Epub 2014 Jul 24.
6
Fetal aortic valvuloplasty for evolving hypoplastic left heart syndrome: postnatal outcomes of the first 100 patients.胎儿主动脉瓣成形术治疗进展性左心发育不全综合征:首批100例患者的产后结局
Circulation. 2014 Aug 19;130(8):638-45. doi: 10.1161/CIRCULATIONAHA.114.009032. Epub 2014 Jul 22.
7
Maternal aspects of fetal cardiac intervention.胎儿心脏介入的母体因素
Ultrasound Obstet Gynecol. 2014 Nov;44(5):532-7. doi: 10.1002/uog.13438. Epub 2014 Sep 22.
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Fetal intervention in right outflow tract obstructive disease: selection of candidates and results.右心流出道梗阻性疾病的胎儿干预:候选者的选择和结果。
Cardiol Res Pract. 2012;2012:592403. doi: 10.1155/2012/592403. Epub 2012 Aug 15.
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